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NCT00002456 · ClinicalTrials.gov registry record · Phase 3

Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantation

A Phase 3 study, sponsored by Fred Hutchinson Cancer Center.

Completed
Registry status
Phase 3
Development phase

NCT00002456: Completed Phase 3 study, sponsored by Fred Hutchinson Cancer Center.

NCT00002456 is a Phase 3 study that has completed, run by Fred Hutchinson Cancer Center. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002456, a Phase 3 study, has completed, sponsored by Fred Hutchinson Cancer Center.

COMPLETED
Registry status
Phase 3
Development phase

Study Summary

RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy used to kill tumor cells. Sometimes the transplanted cells can make an immune response against normal tissues. Methotrexate and cyclosporine may prevent this from happening. PURPOSE: Phase III trial to study the effectiveness of treatment with methotrexate and cyclosporine after bone marrow transplantation to provide protection against acute graft-versus-host disease.

Interventions

  • DRUG methotrexate
  • PROCEDURE allogeneic bone marrow transplantation
  • DRUG cyclosporine

Trial Details

FieldValue
Start Date 1986-05
Est. Completion 2002-04
Phase Phase 3
Fred Hutchinson Cancer Center

483 total trials

What the finished NCT00002456 record still lists

NCT00002456 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.

The record links to 0 conditions, and to 3 interventions - of which methotrexate is the first listed.

NCT00002456 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002456 about?

NCT00002456 is a clinical study titled "Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantation". RATIONALE: Bone marrow transplantation may be able to replace immune cells that were destroyed by chemotherapy used to kill tumor cells. Sometimes the transplanted cells can make an immune response against normal tissues. Methotrexate and cyclosporine may prevent this from happening. PURPOSE: Phase...

What is the current status of trial NCT00002456?

This trial is currently completed. It is a Phase 3 study. The study started on 1986-05. Estimated completion is 2002-04.

What interventions are being tested in trial NCT00002456?

The interventions under investigation include: methotrexate (DRUG), allogeneic bone marrow transplantation (PROCEDURE), cyclosporine (DRUG).

Who is sponsoring clinical trial NCT00002456?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT00002456, the US trial registry maintained by the National Library of Medicine. NCT00002456 (unsized enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.