Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00002423 · ClinicalTrials.gov registry record · Phase 2

A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir

A Phase 2 study, sponsored by Glaxo Wellcome.

Completed
Registry status
Phase 2
Development phase
100
Enrollment target

NCT00002423: Completed Phase 2 study, sponsored by Glaxo Wellcome.

NCT00002423 is a Phase 2 study that has completed, run by Glaxo Wellcome. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00002423, a Phase 2 study, has completed, sponsored by Glaxo Wellcome.

COMPLETED
Registry status
Phase 2
Development phase
100 participants
Enrollment target

Study Summary

This study will compare the safety and effectiveness of two anti-HIV drug combinations in fighting HIV infection in patients whose viral loads (levels of HIV in the blood) rose with other anti-HIV drug treatments.

Interventions

  • DRUG Lamivudine
  • DRUG Indinavir sulfate
  • DRUG Nelfinavir mesylate
  • DRUG Abacavir sulfate
  • DRUG Amprenavir

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 1999-03
Phase Phase 2
Glaxo Wellcome

65 total trials

What the finished NCT00002423 record still lists

NCT00002423 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).

The record links to 0 conditions, and to 5 interventions - of which Lamivudine is the first listed.

NCT00002423 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002423 about?

NCT00002423 is a clinical study titled "A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir". This study will compare the safety and effectiveness of two anti-HIV drug combinations in fighting HIV infection in patients whose viral loads (levels of HIV in the blood) rose with other anti-HIV drug treatments.

What is the current status of trial NCT00002423?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 1999-03.

What interventions are being tested in trial NCT00002423?

The interventions under investigation include: Lamivudine (DRUG), Indinavir sulfate (DRUG), Nelfinavir mesylate (DRUG), Abacavir sulfate (DRUG), Amprenavir (DRUG).

Who is sponsoring clinical trial NCT00002423?

This trial is sponsored by Glaxo Wellcome, which has 65 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002423's enrollment target sits among peer trials

100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01048281 · 100 participants

    Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

  • NCT01161199 · 100 participants

    The Use of Leukapheresis to Support HIV Pathogenesis Studies

  • NCT01327690 · 100 participants · Early Phase 1

    Mental Health in Veterans and Families After Group Therapies

  • NCT01730781 · 100 participants

    Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00002423, the US trial registry maintained by the National Library of Medicine. NCT00002423 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.