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NCT00002338 · ClinicalTrials.gov registry record · Phase 1

The Safety and Effectiveness of 935U83 in HIV-Infected Patients

A Phase 1 study, sponsored by Glaxo Wellcome.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target

NCT00002338: Completed Phase 1 study, sponsored by Glaxo Wellcome.

NCT00002338 is a Phase 1 study that has completed, run by Glaxo Wellcome. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002338, a Phase 1 study, has completed, sponsored by Glaxo Wellcome.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

To assess the safety, tolerance, and steady-state pharmacokinetics of multiple oral doses of 935U83 administered to patients with HIV infection. To obtain preliminary evidence of antiretroviral activity of 935U83. To prospectively evaluate the emergence of in vitro drug resistance. To determine the effects of 935U83 dosing on CD4+ cell counts.

Interventions

  • DRUG Raluridine

Trial Details

FieldValue
Enrollment Target 40 participants
Phase Phase 1
Glaxo Wellcome

65 total trials

What the finished NCT00002338 record still lists

NCT00002338 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).

The record links to 0 conditions, and to 1 intervention - of which Raluridine is the first listed.

NCT00002338 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002338 about?

NCT00002338 is a clinical study titled "The Safety and Effectiveness of 935U83 in HIV-Infected Patients". To assess the safety, tolerance, and steady-state pharmacokinetics of multiple oral doses of 935U83 administered to patients with HIV infection. To obtain preliminary evidence of antiretroviral activity of 935U83. To prospectively evaluate the emergence of in vitro drug resistance. To determine the ...

What is the current status of trial NCT00002338?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants.

What interventions are being tested in trial NCT00002338?

The interventions under investigation include: Raluridine (DRUG).

Who is sponsoring clinical trial NCT00002338?

This trial is sponsored by Glaxo Wellcome, which has 65 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002338's enrollment target sits among peer trials

40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT00002338, the US trial registry maintained by the National Library of Medicine. NCT00002338 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.