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NCT00002316 · ClinicalTrials.gov registry record · Phase 1

The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis

A Phase 1 study, sponsored by Alkermes.

Completed
Registry status
Phase 1
Development phase

NCT00002316: Completed Phase 1 study, sponsored by Alkermes.

NCT00002316 is a Phase 1 study that has completed, run by Alkermes. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002316, a Phase 1 study, has completed, sponsored by Alkermes.

COMPLETED
Registry status
Phase 1
Development phase

Study Summary

To evaluate the safety of escalating doses of RMP-7 administered in persons with HIV infection and cryptococcal meningitis and to determine the MTD of the drug. To evaluate the pharmacokinetics, including cerebrospinal fluid (CSF) penetration, of amphotericin B when administered with RMP-7.

Interventions

  • DRUG Amphotericin B
  • DRUG Lobradimil

Trial Details

FieldValue
Phase Phase 1
Alkermes

66 total trials

What the finished NCT00002316 record still lists

NCT00002316 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.

The record links to 0 conditions, and to 2 interventions - of which Amphotericin B is the first listed.

NCT00002316 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002316 about?

NCT00002316 is a clinical study titled "The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis". To evaluate the safety of escalating doses of RMP-7 administered in persons with HIV infection and cryptococcal meningitis and to determine the MTD of the drug. To evaluate the pharmacokinetics, including cerebrospinal fluid (CSF) penetration, of amphotericin B when administered with RMP-7.

What is the current status of trial NCT00002316?

This trial is currently completed. It is a Phase 1 study.

What interventions are being tested in trial NCT00002316?

The interventions under investigation include: Amphotericin B (DRUG), Lobradimil (DRUG).

Who is sponsoring clinical trial NCT00002316?

This trial is sponsored by Alkermes, which has 66 total clinical trials registered on ClinicalTrials.gov.

Source: ClinicalTrials.gov NCT00002316, the US trial registry maintained by the National Library of Medicine. NCT00002316 (unsized enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.