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NCT00002159 · ClinicalTrials.gov registry record · Phase 3

A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis

A Phase 3 study, sponsored by Janssen.

Completed
Registry status
Phase 3
Development phase
60
Enrollment target

NCT00002159: Completed Phase 3 study, sponsored by Janssen.

NCT00002159 is a Phase 3 study that has completed, run by Janssen. The registered enrollment target is 60 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002159, a Phase 3 study, has completed, sponsored by Janssen.

COMPLETED
Registry status
Phase 3
Development phase
60 participants
Enrollment target

Study Summary

To assess the safety of intravenous itraconazole compared to amphotericin B in HIV positive or negative persons with blastomycosis or histoplasmosis.

Interventions

  • DRUG Itraconazole
  • DRUG Amphotericin B

Trial Details

FieldValue
Enrollment Target 60 participants
Phase Phase 3
Janssen

10 total trials

What the finished NCT00002159 record still lists

NCT00002159 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 2 interventions - of which Itraconazole is the first listed.

NCT00002159 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002159 about?

NCT00002159 is a clinical study titled "A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis". To assess the safety of intravenous itraconazole compared to amphotericin B in HIV positive or negative persons with blastomycosis or histoplasmosis.

What is the current status of trial NCT00002159?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 60 participants.

What interventions are being tested in trial NCT00002159?

The interventions under investigation include: Itraconazole (DRUG), Amphotericin B (DRUG).

Who is sponsoring clinical trial NCT00002159?

This trial is sponsored by Janssen, which has 10 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002159's enrollment target sits among peer trials

60 1804th of 2000 higher than 177 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002159, the US trial registry maintained by the National Library of Medicine. NCT00002159 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.