Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00002128 · ClinicalTrials.gov registry record · Phase 1

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients

A Phase 1 study, sponsored by Gilead Sciences.

Completed
Registry status
Phase 1
Development phase
15
Enrollment target

NCT00002128: Completed Phase 1 study, sponsored by Gilead Sciences.

NCT00002128 is a Phase 1 study that has completed, run by Gilead Sciences. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00002128, a Phase 1 study, has completed, sponsored by Gilead Sciences.

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target

Study Summary

To study the safety, tolerance, and pharmacokinetics of a single dose of bis-POM PMEA (adefovir dipivoxil) when administered by the oral route in patients with HIV infection.

Interventions

  • DRUG Adefovir dipivoxil

Trial Details

FieldValue
Enrollment Target 15 participants
Phase Phase 1
Gilead Sciences

504 total trials

What the finished NCT00002128 record still lists

NCT00002128 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).

The record links to 0 conditions, and to 1 intervention - of which Adefovir dipivoxil is the first listed.

NCT00002128 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002128 about?

NCT00002128 is a clinical study titled "Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients". To study the safety, tolerance, and pharmacokinetics of a single dose of bis-POM PMEA (adefovir dipivoxil) when administered by the oral route in patients with HIV infection.

What is the current status of trial NCT00002128?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants.

What interventions are being tested in trial NCT00002128?

The interventions under investigation include: Adefovir dipivoxil (DRUG).

Who is sponsoring clinical trial NCT00002128?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002128's enrollment target sits among peer trials

15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01889381 · 15 participants · Phase 2

    Human Craniomaxillofacial Allotransplantation

  • NCT02530073 · 15 participants · NA

    Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH

  • NCT02535936 · 15 participants · NA

    Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy

  • NCT02918474 · 15 participants · NA

    Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer

Source: ClinicalTrials.gov NCT00002128, the US trial registry maintained by the National Library of Medicine. NCT00002128 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.