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NCT00001689 · ClinicalTrials.gov registry record · Phase 1

A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemia

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
90
Enrollment target

NCT00001689: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00001689 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 90 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001689, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
90 participants
Enrollment target

Study Summary

The pharmacokinetic behavior of vincristine in pediatric patients has not been well characterized. The present study will obtain detailed information on vincristine pharmacokinetics in patients being treated for standard risk ALL on CCG protocols 1952/1962. A limited sampling strategy will be developed, and the interpatient and intrapatient variability of vincristine pharmacokinetics in children will be studied. A correlation between vincristine neurotoxicity and vincristine pharmacokinetics will be sought.

Interventions

  • DRUG Vincristine

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 1998-01
Est. Completion 2003-11
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00001689

The ClinicalTrials.gov registry entry for NCT00001689 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Vincristine is the first listed.

NCT00001689 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001689 about?

NCT00001689 is a clinical study titled "A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemia". The pharmacokinetic behavior of vincristine in pediatric patients has not been well characterized. The present study will obtain detailed information on vincristine pharmacokinetics in patients being treated for standard risk ALL on CCG protocols 1952/1962. A limited sampling strategy will be develo...

What is the current status of trial NCT00001689?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 1998-01. Estimated completion is 2003-11.

What interventions are being tested in trial NCT00001689?

The interventions under investigation include: Vincristine (DRUG).

Who is sponsoring clinical trial NCT00001689?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.