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NCT00001689 · ClinicalTrials.gov registry record · Phase 1
A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemia
A Phase 1 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 1
- Development phase
- 90
- Enrollment target
NCT00001689: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).
NCT00001689 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 90 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001689, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 90 participants
- Enrollment target
Study Summary
The pharmacokinetic behavior of vincristine in pediatric patients has not been well characterized. The present study will obtain detailed information on vincristine pharmacokinetics in patients being treated for standard risk ALL on CCG protocols 1952/1962. A limited sampling strategy will be developed, and the interpatient and intrapatient variability of vincristine pharmacokinetics in children will be studied. A correlation between vincristine neurotoxicity and vincristine pharmacokinetics will be sought.
Interventions
- DRUG Vincristine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 1998-01 |
| Est. Completion | 2003-11 |
| Phase | Phase 1 |
What the finished NCT00001689 record still lists
NCT00001689 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% higher).
The record links to 0 conditions, and to 1 intervention - of which Vincristine is the first listed.
NCT00001689 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00001689 about?
NCT00001689 is a clinical study titled "A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemia". The pharmacokinetic behavior of vincristine in pediatric patients has not been well characterized. The present study will obtain detailed information on vincristine pharmacokinetics in patients being treated for standard risk ALL on CCG protocols 1952/1962. A limited sampling strategy will be develo...
What is the current status of trial NCT00001689?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 1998-01. Estimated completion is 2003-11.
What interventions are being tested in trial NCT00001689?
The interventions under investigation include: Vincristine (DRUG).
Who is sponsoring clinical trial NCT00001689?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00001689's enrollment target sits among peer trials
90 628th of 2000 higher than 1,352 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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