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NCT00001282 · ClinicalTrials.gov registry record · Phase 2

A Phase I/II Study of the Combination of Azidothymidine and Interleukin-2 (IL-2) in the Treatment of HIV-Infected Patients

A Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
73
Enrollment target

NCT00001282 is a Phase 2 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 73 participants.

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The verdict

NCT00001282, a Phase 2 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
73 participants
Enrollment target

Study Summary

This study will evaluate the long-term toxicity and obtain preliminary information about long-term efficacy of the combination of antiretroviral therapies and interleukin-2 (IL-2), a cytokine with immunomodulatory properties. Currently 73 patients have been approved to receive IL-2 at a starting dose of 18 MIU/d for 5 days. Multiple courses of IL-2 will be administered, at approximately 2 month intervals. Clinical, laboratory, immunologic, and viral parameters will be closely monitored during this time for evidence of toxicity and preliminary evidence of efficacy.

Interventions

  • DRUG Zidovudine (AZT) & Interleukin-2 (IL2)

Trial Details

FieldValue
Enrollment Target 73 participants
Start Date 1991-07
Est. Completion 2002-04
Phase Phase 2

What the Registry Record Tells You About NCT00001282

The ClinicalTrials.gov registry entry for NCT00001282 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Zidovudine (AZT) & Interleukin-2 (IL2) is the first listed.

NCT00001282 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001282 about?

NCT00001282 is a clinical study titled "A Phase I/II Study of the Combination of Azidothymidine and Interleukin-2 (IL-2) in the Treatment of HIV-Infected Patients". This study will evaluate the long-term toxicity and obtain preliminary information about long-term efficacy of the combination of antiretroviral therapies and interleukin-2 (IL-2), a cytokine with immunomodulatory properties. Currently 73 patients have been approved to receive IL-2 at a starting dos...

What is the current status of trial NCT00001282?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 73 participants. The study started on 1991-07. Estimated completion is 2002-04.

What interventions are being tested in trial NCT00001282?

The interventions under investigation include: Zidovudine (AZT) & Interleukin-2 (IL2) (DRUG).

Who is sponsoring clinical trial NCT00001282?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.