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NCT00001272 · ClinicalTrials.gov registry record · Phase 1

A Phase I Study of Taxol, Cisplatin, Cyclophosphamide and Granulocyte Colony-Stimulating Factor (G-CSF) in Previously Nontreated Ovarian Cancer Patients

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
60
Enrollment target

NCT00001272: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00001272 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 60 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001272, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
60 participants
Enrollment target

Study Summary

This is a Phase I study which addresses the feasibility and toxicity of adding taxol to the two drug combination which now comprises the standard of care in newly diagnosed advanced stage ovarian cancer, cisplatin and cyclophosphamide. These drugs will be given in a dose intensive fashion with the colony-stimulating factor, G-CSF. Newly diagnosed patients with ovarian cancer will be treated with this regimen to determine the optimal dose of this combination. The pharmacokinetics of taxol and cisplatin DNA-adducts will be studied as well.

Interventions

  • DRUG taxol

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 1991-09
Est. Completion 2000-05
Phase Phase 1
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00001272 record still lists

NCT00001272 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which taxol is the first listed.

NCT00001272 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00001272 about?

NCT00001272 is a clinical study titled "A Phase I Study of Taxol, Cisplatin, Cyclophosphamide and Granulocyte Colony-Stimulating Factor (G-CSF) in Previously Nontreated Ovarian Cancer Patients". This is a Phase I study which addresses the feasibility and toxicity of adding taxol to the two drug combination which now comprises the standard of care in newly diagnosed advanced stage ovarian cancer, cisplatin and cyclophosphamide. These drugs will be given in a dose intensive fashion with the c...

What is the current status of trial NCT00001272?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 1991-09. Estimated completion is 2000-05.

What interventions are being tested in trial NCT00001272?

The interventions under investigation include: taxol (DRUG).

Who is sponsoring clinical trial NCT00001272?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00001272's enrollment target sits among peer trials

60 831st of 2000 higher than 1,106 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00001272, the US trial registry maintained by the National Library of Medicine. NCT00001272 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.