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NCT00001128 · ClinicalTrials.gov registry record · NA

Treatment of Chronic Cryptosporidiosis in AIDS Patients

A NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Terminated
Registry status
NA
Development phase
16
Enrollment target

NCT00001128 is a NA study that was terminated before completion, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 16 participants.

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The verdict

NCT00001128, a NA study, was terminated before completion, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

TERMINATED
Registry status
NA
Development phase
16 participants
Enrollment target

Study Summary

The purpose of this study is to see if it is safe and effective to add interleukin-12 (IL-12) to the standard drug combination (paromomycin plus azithromycin) used to treat cryptosporidiosis in AIDS patients. Doctors would like to find out if the combination of IL-12, paromomycin, and azithromycin is more effective than paromomycin and azithromycin alone. Cryptosporidiosis is a type of opportunistic (AIDS-related) infection seen in HIV-positive patients as their immune systems weaken. It is caused by a parasite that invades the intestinal tract, and it can cause watery diarrhea, stomach cramps, an upset stomach, or a fever. Antibiotics (paromomycin and azithromycin) are usually used to treat cryptosporidiosis. In this study, doctors will look at the effectiveness of using IL-12. IL-12 is a type of protein naturally produced by certain types of cells of the immune system and is believed to be important for immune function. Doctors hope that IL-12 can help boost the immune system in fighting cryptosporidiosis.

Interventions

  • DRUG Azithromycin
  • DRUG Interleukin-12
  • DRUG Paromomycin sulfate

Trial Details

FieldValue
Enrollment Target 16 participants
Est. Completion 2005-06
Phase NA

What the Registry Record Tells You About NCT00001128

The ClinicalTrials.gov registry entry for NCT00001128 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Azithromycin is the first listed.

NCT00001128 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001128 about?

NCT00001128 is a clinical study titled "Treatment of Chronic Cryptosporidiosis in AIDS Patients". The purpose of this study is to see if it is safe and effective to add interleukin-12 (IL-12) to the standard drug combination (paromomycin plus azithromycin) used to treat cryptosporidiosis in AIDS patients. Doctors would like to find out if the combination of IL-12, paromomycin, and azithromycin i...

What is the current status of trial NCT00001128?

This trial is currently terminated. It is a NA study. The enrollment target is 16 participants. Estimated completion is 2005-06.

What interventions are being tested in trial NCT00001128?

The interventions under investigation include: Azithromycin (DRUG), Interleukin-12 (DRUG), Paromomycin sulfate (DRUG).

Who is sponsoring clinical trial NCT00001128?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.