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NCT00001000 · ClinicalTrials.gov registry record · NA

A Study of Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of Infection

A NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
NA
Development phase
20
Enrollment target

NCT00001000 is a NA study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 20 participants.

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The verdict

NCT00001000, a NA study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

To evaluate the degree and sequence of immunologic enhancement and the cellular resistance to certain infections after a single dose of atvogen (ampligen). In addition, the relationship between activation of immune cells and biochemical markers of that activation will be studied. Treatment of patients with HIV infection must address both the primary viral infection and the subsequent immune deficiency, which is the primary cause of mortality in AIDS. In vitro studies of ampligen have shown it will inhibit HIV infection. Ampligen may also minimize the toxicity of many drugs used in the treatment of AIDS and induce an antiviral state in the brain that may be useful in treating neurologic symptoms of HIV infection. The time course and degree of immunologic response to ampligen remain unknown although they are essential for proper use of the drug in the treatment of HIV infection and perhaps other clinical problems.

Interventions

  • DRUG Ampligen

Trial Details

FieldValue
Enrollment Target 20 participants
Est. Completion 1990-01
Phase NA

What the Registry Record Tells You About NCT00001000

The ClinicalTrials.gov registry entry for NCT00001000 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Ampligen is the first listed.

NCT00001000 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001000 about?

NCT00001000 is a clinical study titled "A Study of Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of Infection". To evaluate the degree and sequence of immunologic enhancement and the cellular resistance to certain infections after a single dose of atvogen (ampligen). In addition, the relationship between activation of immune cells and biochemical markers of that activation will be studied. Treatment of patie...

What is the current status of trial NCT00001000?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. Estimated completion is 1990-01.

What interventions are being tested in trial NCT00001000?

The interventions under investigation include: Ampligen (DRUG).

Who is sponsoring clinical trial NCT00001000?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.