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NCT00000971 · ClinicalTrials.gov registry record · Phase 1

The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS

A Phase 1 study, sponsored by Abbott.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT00000971: Completed Phase 1 study, sponsored by Abbott.

NCT00000971 is a Phase 1 study that has completed, run by Abbott. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000971, a Phase 1 study, has completed, sponsored by Abbott.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

To evaluate three doses of clarithromycin in children with AIDS and Mycobacterium avium complex (MAC) infection who are receiving concurrent antiretroviral therapy. Before more extensive evaluation of this promising drug for treatment of MAC infection in children can be done, it is important to study the pharmacokinetics of this drug in this population, to get information regarding its use in pediatric patients receiving currently available antiretroviral drugs, and to get information on the antimycobacterial activity of this drug.

Interventions

  • DRUG Zidovudine
  • DRUG Clarithromycin
  • DRUG Didanosine

Trial Details

FieldValue
Enrollment Target 24 participants
Phase Phase 1
Abbott

181 total trials

What the finished NCT00000971 record still lists

NCT00000971 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 3 interventions - of which Zidovudine is the first listed.

NCT00000971 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00000971 about?

NCT00000971 is a clinical study titled "The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS". To evaluate three doses of clarithromycin in children with AIDS and Mycobacterium avium complex (MAC) infection who are receiving concurrent antiretroviral therapy. Before more extensive evaluation of this promising drug for treatment of MAC infection in children can be done, it is important to stu...

What is the current status of trial NCT00000971?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants.

What interventions are being tested in trial NCT00000971?

The interventions under investigation include: Zidovudine (DRUG), Clarithromycin (DRUG), Didanosine (DRUG).

Who is sponsoring clinical trial NCT00000971?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00000971's enrollment target sits among peer trials

24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000971, the US trial registry maintained by the National Library of Medicine. NCT00000971 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.