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NCT00000844 · ClinicalTrials.gov registry record · NA

A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Three Preparations of Low-Dose Oral Alpha Interferon in HIV-Infected Patients With CD4+ Counts >= 50 and <= 350 Cells/mm3

A NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
NA
Development phase
560
Enrollment target

NCT00000844: Completed NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00000844 is a NA study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 560 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000844, a NA study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
NA
Development phase
560 participants
Enrollment target

Study Summary

To evaluate the effects of three preparations of low-dose oral interferon alpha (i.e., Alferon LDO, Veldona, and Ferimmune) on HIV symptoms in HIV-infected patients. To evaluate differences in response to oral interferon alpha according to gender, race/ethnicity, and use of antiretrovirals. Previous or ongoing clinical trials to test the efficacy of low-dose oral interferon alpha have produced different results, and it is not clear whether the differences were due to the interferon alpha products used or to problems in the study design. Therefore, three preparations will be compared to evaluate their potential efficacies.

Interventions

  • DRUG Interferon alfa-n1
  • DRUG Interferon alfa-n3

Trial Details

FieldValue
Enrollment Target 560 participants
Est. Completion 2002-06
Phase NA

What the finished NCT00000844 record still lists

NCT00000844 is an interventional study that assigns participants to a tested intervention. The registered 560 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 2 interventions - of which Interferon alfa-n1 is the first listed.

NCT00000844 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00000844 about?

NCT00000844 is a clinical study titled "A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Three Preparations of Low-Dose Oral Alpha Interferon in HIV-Infected Patients With CD4+ Counts >= 50 and <= 350 Cells/mm3". To evaluate the effects of three preparations of low-dose oral interferon alpha (i.e., Alferon LDO, Veldona, and Ferimmune) on HIV symptoms in HIV-infected patients. To evaluate differences in response to oral interferon alpha according to gender, race/ethnicity, and use of antiretrovirals. Previou...

What is the current status of trial NCT00000844?

This trial is currently completed. It is a NA study. The enrollment target is 560 participants. Estimated completion is 2002-06.

What interventions are being tested in trial NCT00000844?

The interventions under investigation include: Interferon alfa-n1 (DRUG), Interferon alfa-n3 (DRUG).

Who is sponsoring clinical trial NCT00000844?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00000844's enrollment target sits among peer trials

560 181st of 2000 higher than 1,818 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000844, the US trial registry maintained by the National Library of Medicine. NCT00000844 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.