Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00000655 · ClinicalTrials.gov registry record · Phase 2

A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients

A Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
300
Enrollment target

NCT00000655 is a Phase 2 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 300 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00000655, a Phase 2 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
300 participants
Enrollment target

Study Summary

To evaluate the effectiveness of atovaquone (566C80) compared to a standard antipneumocystis agent, (SMX/TMP), for the treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in AIDS patients. To compare the safety of short-term (21 days) treatment with 566C80 and SMX/TMP in AIDS patients with an acute episode of PCP. Standard therapies for acute treatment of PCP involve either SMX/TMP or pentamidine isetionate. Although both treatments are equally effective, side effects prevent completion of therapy in 11-55 percent of patients.

Interventions

  • DRUG Atovaquone
  • DRUG Sulfamethoxazole-Trimethoprim

Trial Details

FieldValue
Enrollment Target 300 participants
Phase Phase 2

What the Registry Record Tells You About NCT00000655

The ClinicalTrials.gov registry entry for NCT00000655 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Atovaquone is the first listed.

NCT00000655 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00000655 about?

NCT00000655 is a clinical study titled "A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients". To evaluate the effectiveness of atovaquone (566C80) compared to a standard antipneumocystis agent, (SMX/TMP), for the treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in AIDS patients. To compare the safety of short-term (21 days) treatment with 566C80 and SMX/TMP in AIDS patients...

What is the current status of trial NCT00000655?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 300 participants.

What interventions are being tested in trial NCT00000655?

The interventions under investigation include: Atovaquone (DRUG), Sulfamethoxazole-Trimethoprim (DRUG).

Who is sponsoring clinical trial NCT00000655?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.