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NCT00000646 · ClinicalTrials.gov registry record · Phase 1

Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
54
Enrollment target

NCT00000646 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 54 participants.

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The verdict

NCT00000646, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
54 participants
Enrollment target

Study Summary

To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.

Interventions

  • DRUG Pentoxifylline

Trial Details

FieldValue
Enrollment Target 54 participants
Est. Completion 1993-03
Phase Phase 1

What the Registry Record Tells You About NCT00000646

The ClinicalTrials.gov registry entry for NCT00000646 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Pentoxifylline is the first listed.

NCT00000646 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00000646 about?

NCT00000646 is a clinical study titled "Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS". To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.

What is the current status of trial NCT00000646?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 54 participants. Estimated completion is 1993-03.

What interventions are being tested in trial NCT00000646?

The interventions under investigation include: Pentoxifylline (DRUG).

Who is sponsoring clinical trial NCT00000646?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.