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NCT00000431 · ClinicalTrials.gov registry record · Phase 1
Preliminary Testing of New Treatment for Chronic Leg Wounds
A Phase 1 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT00000431: Completed Phase 1 study, sponsored by University of Pennsylvania.
NCT00000431 is a Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 24 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000431, a Phase 1 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
Most chronic (long-lasting) wounds of the leg (also known as venous ulcers) fail to heal in a reasonable period of time. Although researchers have made great progress in understanding how the body repairs wounds, attempts to develop new treatments have been disappointing. In general, treatments based on recent findings about the details of wound repair have not greatly reduced the number of people who have chronic wounds. The long-term goal of this study is to evaluate a new approach for healing a chronic wound. Current methods of directly applying substances that are involved in wound healing to a chronic wound do not cause enough healing. PDGF-B (platelet-derived growth factor B), a factor associated with wound healing, might dramatically enhance healing if a genetically engineered virus is injected into the wound that causes cells in the wound to produce PDGF-B in large quantities.
Interventions
- DRUG PDGF-B/Ad5
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2005-01 |
| Est. Completion | 2011-03 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00000431
The ClinicalTrials.gov registry entry for NCT00000431 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which PDGF-B/Ad5 is the first listed.
NCT00000431 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00000431 about?
NCT00000431 is a clinical study titled "Preliminary Testing of New Treatment for Chronic Leg Wounds". Most chronic (long-lasting) wounds of the leg (also known as venous ulcers) fail to heal in a reasonable period of time. Although researchers have made great progress in understanding how the body repairs wounds, attempts to develop new treatments have been disappointing. In general, treatments base...
What is the current status of trial NCT00000431?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2005-01. Estimated completion is 2011-03.
What interventions are being tested in trial NCT00000431?
The interventions under investigation include: PDGF-B/Ad5 (DRUG).
Who is sponsoring clinical trial NCT00000431?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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