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NCT00000406 · ClinicalTrials.gov registry record · Phase 2
Effects of Strength Training on Knee Osteoarthritis
A Phase 2 study, sponsored by Indiana University.
- Completed
- Registry status
- Phase 2
- Development phase
- 280
- Enrollment target
NCT00000406: Completed Phase 2 study, sponsored by Indiana University.
NCT00000406 is a Phase 2 study that has completed, run by Indiana University. The registered enrollment target is 280 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (111% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000406, a Phase 2 study, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 280 participants
- Enrollment target
Study Summary
To understand the effects of leg strengthening exercise, we will study the effects of strength training of the legs in four groups of people: (1) osteoarthritis (OA) with knee pain; (2) OA without knee pain; (3) no OA but elderly with knee pain; and (4) normal elderly with no OA or knee pain. In each of the first three groups, we will look at whether people who do strength training have less pain and/or slower progression of x-ray signs of OA over 30 months than people who perform nonstrengthening, range-of-motion exercises. We are including the fourth group to find out whether people with OA (groups 1 \& 2) have the same response to strength training as healthy elderly people, and whether those with knee pain (groups 1 \& 3) have the same response to training as those without joint pain.
Interventions
- PROCEDURE Progressive resistance exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 280 participants |
| Start Date | 1977-09 |
| Est. Completion | 2006-11 |
| Phase | Phase 2 |
What the finished NCT00000406 record still lists
NCT00000406 is an interventional study that assigns participants to a tested intervention. The registered 280 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (111% higher).
The record links to 0 conditions, and to 1 intervention - of which Progressive resistance exercise is the first listed.
NCT00000406 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00000406 about?
NCT00000406 is a clinical study titled "Effects of Strength Training on Knee Osteoarthritis". To understand the effects of leg strengthening exercise, we will study the effects of strength training of the legs in four groups of people: (1) osteoarthritis (OA) with knee pain; (2) OA without knee pain; (3) no OA but elderly with knee pain; and (4) normal elderly with no OA or knee pain. In eac...
What is the current status of trial NCT00000406?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 280 participants. The study started on 1977-09. Estimated completion is 2006-11.
What interventions are being tested in trial NCT00000406?
The interventions under investigation include: Progressive resistance exercise (PROCEDURE).
Who is sponsoring clinical trial NCT00000406?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00000406's enrollment target sits among peer trials
280 196th of 2000 higher than 1,800 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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