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NCT00000399 · ClinicalTrials.gov registry record · Phase 2
Bone Estrogen Strength Training
A Phase 2 study, sponsored by University of Arizona.
- Completed
- Registry status
- Phase 2
- Development phase
- 300
- Enrollment target
NCT00000399: Completed Phase 2 study, sponsored by University of Arizona.
NCT00000399 is a Phase 2 study that has completed, run by University of Arizona. The registered enrollment target is 300 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (126% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000399, a Phase 2 study, has completed, sponsored by University of Arizona.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 300 participants
- Enrollment target
Study Summary
We started the Bone, Estrogen, Strength Training (BEST) study in the fall of 1995 at the University of Arizona, Tucson, Arizona. The BEST study is the largest of its kind. It looks at the effects of hormone replacement therapy and strength training exercise on bone mineral density. (Bone mineral density affects bone strength and the risk of osteoporosis.) Six groups of about 300 women each participated in this osteoporosis prevention study. In 1998, the BEST study received additional funding to examine for another 2 years the long-term effects of strength training on bone mineral density. By 2001 we will have finished analyzing the results for all study groups on the 1-year effects of exercise on bone, as well as additional analyses on the effects of 2, 3, and 4 years of strength training and weight-bearing exercise on bone.
Interventions
- PROCEDURE Strength training
- DRUG Hormone replacement therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 1995-08 |
| Est. Completion | 2001-01 |
| Phase | Phase 2 |
What the finished NCT00000399 record still lists
NCT00000399 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (126% higher).
The record links to 0 conditions, and to 2 interventions - of which Strength training is the first listed.
NCT00000399 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00000399 about?
NCT00000399 is a clinical study titled "Bone Estrogen Strength Training". We started the Bone, Estrogen, Strength Training (BEST) study in the fall of 1995 at the University of Arizona, Tucson, Arizona. The BEST study is the largest of its kind. It looks at the effects of hormone replacement therapy and strength training exercise on bone mineral density. (Bone mineral den...
What is the current status of trial NCT00000399?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 300 participants. The study started on 1995-08. Estimated completion is 2001-01.
What interventions are being tested in trial NCT00000399?
The interventions under investigation include: Strength training (PROCEDURE), Hormone replacement therapy (DRUG).
Who is sponsoring clinical trial NCT00000399?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00000399's enrollment target sits among peer trials
300 167th of 2000 higher than 1,813 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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