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ClinicalTrials.gov 7 recruiting now official registry

Recurrent B Acute Lymphoblastic Leukemia clinical trials

Every US clinical trial registered for Recurrent B Acute Lymphoblastic Leukemia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

13 US clinical trials · 7 currently recruiting

The research picture

Recurrent B Acute Lymphoblastic Leukemia has 13 registered US clinical trials, 7 of them open to new participants right now — about 54% of the total.

7
recruiting participants now
54%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: National Cancer Institute (NCI)

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 2 461 participants

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

National Cancer Institute (NCI)

NCT04546399

RECRUITING Phase 1 276 participants

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

M.D. Anderson Cancer Center

NCT01371630

RECRUITING Phase 2 80 participants

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Children's Oncology Group

NCT02981628

RECRUITING Phase 2 64 participants

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT03739814

RECRUITING Phase 1 54 participants

Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

Sumithira Vasu

NCT05418088

RECRUITING Phase 1 30 participants

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

St. Jude Children's Research Hospital

NCT06777979

RECRUITING Phase 1 20 participants

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

OHSU Knight Cancer Institute

NCT04872790

ACTIVE NOT RECRUITING Phase 3 669 participants

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT02101853

ACTIVE NOT RECRUITING Phase 1 50 participants

Low-Intensity Chemotherapy and Venetoclax in Treating Patients With Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia

M.D. Anderson Cancer Center

NCT03808610

ACTIVE NOT RECRUITING Phase 1 40 participants

Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia

ECOG-ACRIN Cancer Research Group

NCT03504644

ACTIVE NOT RECRUITING Phase 2 40 participants

Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease

M.D. Anderson Cancer Center

NCT03441061

ACTIVE NOT RECRUITING Phase 1 28 participants

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT02879695

COMPLETED Phase 1 7 participants

Palbociclib and Dexamethasone in Treating Participants With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT03472573

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 4
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent B Acute Lymphoblastic Leukemia Trial Landscape

ClinicalTrials.gov lists 13 US studies indexed under Recurrent B Acute Lymphoblastic Leukemia, and 7 of those are currently open to recruitment — roughly 54% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Recurrent B Acute Lymphoblastic Leukemia shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Recurrent B Acute Lymphoblastic Leukemia is led by National Cancer Institute (NCI) with 4 indexed trials, alongside 7 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent B Acute Lymphoblastic Leukemia?

PlainTrial tracks 13 US clinical trials for Recurrent B Acute Lymphoblastic Leukemia, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent B Acute Lymphoblastic Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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