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Posttraumatic Stress Disorder clinical trials
39 of 119 indexed Posttraumatic Stress Disorder trials are currently recruiting.
119 US clinical trials · 39 currently recruiting
Posttraumatic Stress Disorder is the subject of 119 registered US clinical trials on ClinicalTrials.gov, 39 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 16 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 26 of these trials.
The research picture
Posttraumatic Stress Disorder has 119 registered US clinical trials, 39 of them open to new participants right now, about 33% of the total.
- 39
- recruiting participants now
- 33%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 26
- top sponsor: VA Office of Research and Development
Active & Recent Trials
119 total, page 3 of 3
Online Intervention to Promote Resilience to Traumatic Stress During Pregnancy
University of Illinois at Chicago
NCT04992767
Mobile Intervention for Veterans With PTSD and Anger
VA Office of Research and Development
NCT03733028
MGH Trauma-related Nightmares SDI Study
Massachusetts General Hospital
NCT05195684
A Study of Sertraline to Prevent PTSD
Massachusetts General Hospital
NCT00182078
A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol
Massachusetts General Hospital
NCT00709735
MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder
Lykos Therapeutics
NCT00090064
Treating Co-Morbid Sleep Difficulties in Veterans With Posttraumatic Stress Disorder (PTSD): A Pilot Study
Durham VA Medical Center
NCT00734799
Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents
State University of New York at Buffalo
NCT03737383
Building Resilience After Childhood Emergencies (BRACE)
Case Western Reserve University
NCT02898883
An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder
Lori Davis, MD
NCT01587118
Reducing PTSD in Hospitalized Burn Patients
University of Southern California
NCT02026037
A Self-Management Program for Completers of Trauma-Focused Therapy for PTSD
VA Office of Research and Development
NCT03225859
Reducing Cannabis Overuse With Prazosin
VA Puget Sound Health Care System
NCT04721353
Norepinephrine Transporter Availability in PTSD
Emory University
NCT01799837
Narrative Exposure Therapy (NET)
VA Office of Research and Development
NCT03777553
Targeted Strategies to Accelerate Evidence-Based Psychotherapy (EBP) Implementation in Military Settings
Palo Alto Veterans Institute for Research
NCT03663452
Using Attentional Bias Modification to Address Trauma Symptoms
University of Nebraska Lincoln
NCT02615717
Lifespan Integration for Posttraumatic Stress Disorder From an Auto Accident
Argosy University
NCT01263067
Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU)
Stanford University
NCT00186472
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 9 |
| Phase 3 | 3 |
| Phase 4 | 6 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Posttraumatic Stress Disorder Trial Landscape
119 indexed Posttraumatic Stress Disorder studies · 39 recruiting (33%).
Phase mix: 9 late (III/IV) vs 16 early (I/II).
Top sponsor: VA Office of Research and Development (26 trials), 9 others listed. 19 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Posttraumatic Stress Disorder?
PlainTrial tracks 119 US clinical trials for Posttraumatic Stress Disorder, of which 39 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Posttraumatic Stress Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.