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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Kidney Failure: early-phase trial registry

5 of 19 indexed Kidney Failure trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 5 currently recruiting · #902 of 28,707 conditions by registered trial count

Kidney Failure: 19 US clinical trials tracked, 5 recruiting.

Kidney Failure is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Keryx Biopharmaceuticals, running 1 of these trials.

Enrollment posture brief

Registry condition kidney-failure

OPEN 5 | RECR 26% | LATE 2 | EARLY 6 | RANK #902 | SPON 1

Nearest open-share peer: Concussion, Mild (26% recruiting · 19 trials)

Amyotrophic Lateral Sclerosi52.6%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%Kidney Failure (this)26%
Open-enrollment share among volume-matched conditions near Kidney Failure

Kidney Failure lists 5 open slots (26% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Kidney Failure on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Kidney Failure is recruiting below its size-band peers.

    5 of 19 indexed trials (26.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Kidney Failure trials is spread across many organizations.

    Keryx Biopharmaceuticals accounts for 1 of 19 trials (5.3%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Typical Kidney Failure enrolment sits around 99 participants.

    Median target enrolment is 99 among the 19 trials that report a genuine target (sentinel values excluded). 10 of those (52.6%) plan for fewer than 100 participants.

  4. Kidney Failure research is mostly interventional.

    14 interventional and 5 observational studies make up this index (73.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 21Phase 32

Open and recent trials

19 total, page 1 of 1

RECRUITING 5,000 participants

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

Wake Forest University Health Sciences

NCT03615235

RECRUITING NA 133 participants

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

W.L.Gore & Associates

NCT04671771

RECRUITING Phase 1 20 participants

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06056102

RECRUITING Early Phase 1 12 participants

Tolerance Through Mixed Chimerism (Sip-Tego)

Tatsuo Kawai, MD, PhD

NCT06972069

RECRUITING NA 5 participants

Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

University of California, Los Angeles

NCT06337942

ACTIVE NOT RECRUITING 2,050 participants

Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure

Beth Israel Deaconess Medical Center

NCT02194582

ACTIVE NOT RECRUITING NA 775 participants

Expanding Live Donor Kidney Transplantation Through Advocacy Training and Social Media

Johns Hopkins University

NCT03099434

ACTIVE NOT RECRUITING NA 31 participants

Hepatitis C Virus (HCV) Positive Kidney Grafts in HCV Negative Recipients

Loma Linda University

NCT04605679

ACTIVE NOT RECRUITING Phase 1 20 participants

Delayed Tolerance Through Mixed Chimerism

Massachusetts General Hospital

NCT05900401

COMPLETED 634 participants

The Drug Induced Renal Injury Consortium

Ravindra Mehta

NCT02159209

COMPLETED 621 participants

Screening for Patients Needing Kidney, Kidney-Pancreas, or Islet-Cell Transplant

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00001859

COMPLETED Phase 3 441 participants

A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis

Keryx Biopharmaceuticals

NCT01191255

COMPLETED NA 425 participants

Healthy.io Method Comparison & User Performance Study

Healthy.io

NCT02785445

COMPLETED Phase 3 149 participants

Study of MB-102 (Relmapirazin) and the Use of the MediBeacon® Transdermal GFR Measurement System Using the TGFR Reusable Sensor With Disposable Adhesive Ring

MediBeacon

NCT05777174

COMPLETED Phase 2 99 participants

Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation

Wright State University

NCT00906204

COMPLETED Phase 1 70 participants

C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI

Cedars-Sinai Medical Center

NCT02134314

COMPLETED Phase 1 62 participants

Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD

University of Utah

NCT05614115

COMPLETED 12 participants

Blood Volume Analysis and Renal Outcomes in Hemodialysis

VA New York Harbor Healthcare System

NCT02717533

COMPLETED NA 12 participants

Acute Effects of Intradialytic Exercise on Cardiovascular Function in Hemodialysis Patients

University of Illinois at Urbana-Champaign

NCT02753868

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 1
Phase 3 2

Named interventions

Most-linked intervention names on Kidney Failure records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fludarabine Drug
2 trials
Cyclophosphamide Drug
2 trials
Hemodialysis treatment Procedure
1 trials
MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR) Device
1 trials
ferric citrate, ca acetate, sevelamer carbonate, placebo Drug
1 trials
ACON U500 Mission® U500 Urine Analyzer Device
1 trials
Dip.io Home Based Dipstick Analyzer Device
1 trials
dry weight adjustment Other
1 trials

US sites by state

Facility locations filed on Kidney Failure trials. A trial with sites in several states counts in each.

Massachusetts 7 trials
New York 6 trials
California 6 trials
Maryland 5 trials
Illinois 4 trials
Georgia 4 trials
Texas 3 trials
Pennsylvania 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Kidney Failure page

19 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Kidney Failure condition card totals 19 registered trials; most-linked intervention Fludarabine; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.