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ClinicalTrials.gov 5 recruiting now official registry

Kidney Failure clinical trials

Every US clinical trial registered for Kidney Failure — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

19 US clinical trials · 5 currently recruiting

The research picture

Kidney Failure has 19 registered US clinical trials, 5 of them open to new participants right now — about 26% of the total.

5
recruiting participants now
26%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
1
top sponsor: Keryx Biopharmaceuticals

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 5,000 participants

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

Wake Forest University Health Sciences

NCT03615235

RECRUITING NA 133 participants

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

W.L.Gore & Associates

NCT04671771

RECRUITING Phase 1 20 participants

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06056102

RECRUITING Early Phase 1 12 participants

Tolerance Through Mixed Chimerism (Sip-Tego)

Tatsuo Kawai, MD, PhD

NCT06972069

RECRUITING NA 5 participants

Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

University of California, Los Angeles

NCT06337942

ACTIVE NOT RECRUITING 2,050 participants

Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure

Beth Israel Deaconess Medical Center

NCT02194582

ACTIVE NOT RECRUITING NA 775 participants

Expanding Live Donor Kidney Transplantation Through Advocacy Training and Social Media

Johns Hopkins University

NCT03099434

ACTIVE NOT RECRUITING NA 31 participants

Hepatitis C Virus (HCV) Positive Kidney Grafts in HCV Negative Recipients

Loma Linda University

NCT04605679

ACTIVE NOT RECRUITING Phase 1 20 participants

Delayed Tolerance Through Mixed Chimerism

Massachusetts General Hospital

NCT05900401

COMPLETED 634 participants

The Drug Induced Renal Injury Consortium

Ravindra Mehta

NCT02159209

COMPLETED 621 participants

Screening for Patients Needing Kidney, Kidney-Pancreas, or Islet-Cell Transplant

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00001859

COMPLETED Phase 3 441 participants

A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis

Keryx Biopharmaceuticals

NCT01191255

COMPLETED NA 425 participants

Healthy.io Method Comparison & User Performance Study

Healthy.io

NCT02785445

COMPLETED Phase 3 149 participants

Study of MB-102 (Relmapirazin) and the Use of the MediBeacon® Transdermal GFR Measurement System Using the TGFR Reusable Sensor With Disposable Adhesive Ring

MediBeacon

NCT05777174

COMPLETED Phase 2 99 participants

Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation

Wright State University

NCT00906204

COMPLETED Phase 1 70 participants

C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI

Cedars-Sinai Medical Center

NCT02134314

COMPLETED Phase 1 62 participants

Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD

University of Utah

NCT05614115

COMPLETED 12 participants

Blood Volume Analysis and Renal Outcomes in Hemodialysis

VA New York Harbor Healthcare System

NCT02717533

COMPLETED NA 12 participants

Acute Effects of Intradialytic Exercise on Cardiovascular Function in Hemodialysis Patients

University of Illinois at Urbana-Champaign

NCT02753868

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 1
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Kidney Failure Trial Landscape

ClinicalTrials.gov lists 19 US studies indexed under Kidney Failure, and 5 of those are currently open to recruitment — roughly 26% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Kidney Failure shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Kidney Failure is led by Keryx Biopharmaceuticals with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Kidney Failure?

PlainTrial tracks 19 US clinical trials for Kidney Failure, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Kidney Failure?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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