Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Heartburn: later-stage trial registry
3 of 10 indexed Heartburn trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 3 currently recruiting · #1,724 of 28,707 conditions by registered trial count
Heartburn: 10 US clinical trials tracked, 3 recruiting.
Heartburn is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Novartis, running 2 of these trials.
Enrollment posture brief
Registry condition heartburn
OPEN 3 | RECR 30% | LATE 6 | EARLY 1 | RANK #1724 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adrenocortical Carcinoma (30% recruiting · 10 trials)
Heartburn lists 3 open slots (30% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Heartburn on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Heartburn is recruiting below its size-band peers.
3 of 10 indexed trials (30%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Heartburn research.
Novartis accounts for 2 of 10 trials (20%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Heartburn enrolment sits around 576 participants.
Median target enrolment is 576 among the 10 trials that report a genuine target (sentinel values excluded). 3 of those (30%) plan for fewer than 100 participants.
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Heartburn research is mostly interventional.
8 interventional and 2 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
Phathom Pharmaceuticals
NCT06660342
Domperidone in Treating Patients With Gastrointestinal Disorders
M.D. Anderson Cancer Center
NCT01696734
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Mayo Clinic
NCT05976165
E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers
Eisai
NCT00236184
E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers
Eisai
NCT00236197
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn
Novartis
NCT00389948
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn
Novartis
NCT00390390
Acid-Associated Heartburn Symptoms and Dose of Esomeprazole
AstraZeneca
NCT00206024
Confocal Laser Microscopy in Non Erosive Reflux Disease
Mayo Clinic
NCT00588939
Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets
Takeda
NCT02096458
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 5 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Heartburn records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Heartburn trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Heartburn page
10 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Heartburn trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Novartis sponsors the most Heartburn trials on record, review their full trial history before evaluating a specific study. See Novartis's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Heartburn condition card totals 10 registered trials; most-linked intervention rabeprazole sodium; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.