Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Heartburn
Open-data reference.
10 US clinical trials · 3 currently recruiting
Active & Recent Trials
A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
Phathom Pharmaceuticals
NCT06660342
Domperidone in Treating Patients With Gastrointestinal Disorders
M.D. Anderson Cancer Center
NCT01696734
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Mayo Clinic
NCT05976165
E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers
Eisai
NCT00236184
E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers
Eisai
NCT00236197
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn
Novartis
NCT00389948
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn
Novartis
NCT00390390
Acid-Associated Heartburn Symptoms and Dose of Esomeprazole
AstraZeneca
NCT00206024
Confocal Laser Microscopy in Non Erosive Reflux Disease
Mayo Clinic
NCT00588939
Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets
Takeda
NCT02096458
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 3 | 5 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Heartburn Trial Landscape
ClinicalTrials.gov lists 10 US studies indexed under Heartburn, and 3 of those are currently open to recruitment — roughly 30% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Heartburn shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Heartburn is led by Novartis with 2 indexed trials, alongside 6 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Heartburn?
PlainTrial tracks 10 US clinical trials for Heartburn, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Heartburn?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.