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Heartburn clinical trials
3 of 10 indexed Heartburn trials are currently recruiting.
10 US clinical trials · 3 currently recruiting
Heartburn is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Novartis, running 2 of these trials.
The research picture
Heartburn has 10 registered US clinical trials, 3 of them open to new participants right now, about 30% of the total.
- 3
- recruiting participants now
- 30%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Novartis
Active & Recent Trials
10 total, page 1 of 1
A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
Phathom Pharmaceuticals
NCT06660342
Domperidone in Treating Patients With Gastrointestinal Disorders
M.D. Anderson Cancer Center
NCT01696734
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Mayo Clinic
NCT05976165
E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers
Eisai
NCT00236184
E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers
Eisai
NCT00236197
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn
Novartis
NCT00389948
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn
Novartis
NCT00390390
Acid-Associated Heartburn Symptoms and Dose of Esomeprazole
AstraZeneca
NCT00206024
Confocal Laser Microscopy in Non Erosive Reflux Disease
Mayo Clinic
NCT00588939
Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets
Takeda
NCT02096458
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 5 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Heartburn Trial Landscape
10 indexed Heartburn studies · 3 recruiting (30%).
Phase mix: 6 late (III/IV) vs 1 early (I/II).
Top sponsor: Novartis (2 trials), 6 others listed. 10 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Heartburn?
PlainTrial tracks 10 US clinical trials for Heartburn, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Heartburn?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.