Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1,251Healthy1,096Obesity1,057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
A2,832B1,103C2,954D1,173E990F827G777H1,716I1,113J83K188L1,242M2,127N1,045O826P2,857Q24R1,694S3,019T976U530V511W241X47Y19Z17
Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Localized Prostate Carcinoma 15
Localized Renal Pelvis and Ureter Urothelial Carcinoma 2
Localized Resectable Adult Liver Carcinoma 1
Localized Resectable Adult Primary Liver Cancer 1
Localized Resectable Neuroblastoma 5
Localized Skin Lesion 1
Localized Unresectable Adult Primary Liver Cancer 6
Localized Unresectable Neuroblastoma 4
Locally Advanced 7
Locally Advanced (Inoperable) or Metastatic Breast Cancer 2
Locally Advanced (Unresectable) or Metastatic Adenocarcinoma of the Gastric and Gastro-esophageal Junction 1
Locally Advanced / Metastatic Solid Tumors 1
Locally Advanced Adenocarcinoma 1
Locally Advanced Adrenal Cortex Carcinoma 1
Locally Advanced Adrenal Cortical Carcinoma 1
Locally Advanced Alveolar Soft Part Sarcoma 1
Locally Advanced Basal Cell Carcinoma 3
Locally Advanced Bladder Carcinoma 3
Locally Advanced Bladder Urothelial Carcinoma 9
Locally Advanced Breast Cancer 10
Locally Advanced Breast Cancer (LABC) 1
Locally Advanced Breast Carcinoma 9
Locally Advanced Cancer 1
Locally Advanced Carcinoma 2
Locally Advanced Cervical Adenocarcinoma 1
Locally Advanced Cervical Adenosquamous Carcinoma 1
Locally Advanced Cervical Cancer 2
Locally Advanced Cervical Carcinoma 3
Locally Advanced Cervical Squamous Cell Carcinoma 1
Locally Advanced Cervical Squamous Cell Carcinoma, Not Otherwise Specified 1
Locally Advanced Cholangiocarcinoma 2
Locally Advanced Chondrosarcoma 1
Locally Advanced Clear Cell Renal Cell Carcinoma 3
Locally Advanced Colorectal Carcinoma 2
Locally Advanced Cutaneous Melanoma 1
Locally Advanced Cutaneous Squamous Cell Carcinoma 3
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck 1
Locally Advanced Dedifferentiated Liposarcoma 1
Locally Advanced Differentiated Thyroid Gland Carcinoma 1
Locally Advanced Digestive System Neuroendocrine Neoplasm 1
Locally Advanced Digestive System Neuroendocrine Tumor G1 1
Locally Advanced Esophageal Adenocarcinoma 1
Locally Advanced Esophageal Carcinoma 1
Locally Advanced Extraskeletal Myxoid Chondrosarcoma 1
Locally Advanced Gastric Adenocarcinoma 1
Locally Advanced Gastric Carcinoma 3
Locally Advanced Gastroesophageal Junction Adenocarcinoma 5
Locally Advanced Gastrointestinal Stromal Tumor 1
Locally Advanced Head and Neck Cancer 2
Locally Advanced Head and Neck Carcinoma 3