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NCT07453537 · ClinicalTrials.gov registry record · NA
Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults
A NA study of Physiological Stress and Motor Activity, sponsored by University of Florida.
- Recruiting
- Registry status
- NA
- Development phase
- 84
- Enrollment target
- 1
- Study location
NCT07453537: Recruiting NA study of Physiological Stress and Motor Activity, sponsored by University of Florida.
NCT07453537 is a NA study of Physiological Stress and Motor Activity that is actively recruiting participants, run by University of Florida. The registered enrollment target is 84 participants, above the 59-participant average among 6 other Physiological Stress trials with a reported enrollment target (42% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07453537, a NA study of Physiological Stress and Motor Activity, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized, double-blind, placebo-controlled clinical trial evaluates whether 70 days of daily cranberry juice consumption improves cognitive performance and motor accuracy and reduces psychological and physiological stress responses during a motor-cognitive dual-task multitasking challenge in healthy adults aged 30-55 (Aim 1). It is hypothesized that chronic cranberry juice intake will enhance dual-task performance and attenuate stress reactivity (Hypothesis 1). It is further hypothesized that cranberry juice will mitigate multitasking-related fatigue, mood fluctuations, and cognitive impairment, accompanied by favorable changes in circulating stress biomarkers and stress-regulatory neurochemical pathways (Aim 2/Hypothesis 2). Finally, the study incorporates gut analysis to determine whether cranberry juice induces beneficial shifts in the gut microbiota and microbial metabolites (e.g., SCFAs) and whether these changes are associated with improved cognitive and stress-related outcomes, consistent with a microbiome-gut-brain axis mechanism (Aim 3/Hypothesis 3).
Primary Outcome
Total number of correct subtractions during the multitasking cognitive task Measure Description: Counting backward aloud from a random number between 800-999 by 3, 7, and 17; performance scored as total correct subtractions across the task.
Conditions Studied
Interventions
- OTHER Cranberry juice
- OTHER Placebo juice
Study Locations (1)
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2026-04-01 |
| Est. Completion | 2029-08-01 |
| Phase | NA |
What NCT07453537 shows while recruiting
NCT07453537 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, above the 59-participant average among 6 other Physiological Stress trials with a reported enrollment target (42% higher).
The record links to 6 conditions, with Physiological Stress appearing as the primary indexed condition, and to 2 interventions - of which Cranberry juice is the first listed.
NCT07453537 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT07453537 about?
NCT07453537 is a clinical study titled "Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults". This randomized, double-blind, placebo-controlled clinical trial evaluates whether 70 days of daily cranberry juice consumption improves cognitive performance and motor accuracy and reduces psychological and physiological stress responses during a motor-cognitive dual-task multitasking challenge in ...
What is the current status of trial NCT07453537?
This trial is currently recruiting. It is a NA study. The enrollment target is 84 participants. The study started on 2026-04-01. Estimated completion is 2029-08-01.
What conditions does trial NCT07453537 study?
This clinical trial studies the following conditions: Physiological Stress, Motor Activity, Mental Stress, Cognitive Symptoms, Stress Response.
What interventions are being tested in trial NCT07453537?
The interventions under investigation include: Cranberry juice (OTHER), Placebo juice (OTHER).
Who is sponsoring clinical trial NCT07453537?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07453537 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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