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NCT07433322 · ClinicalTrials.gov registry record · NA

Alveolar Ridge Preservation (ARP) in the Posterior Maxilla After the Extraction of Maxillary Molars

A NA study of Alveolar Bone Loss, sponsored by Virginia Commonwealth University.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT07433322 is a NA study of Alveolar Bone Loss that is actively recruiting participants, run by Virginia Commonwealth University. The registered enrollment target is 40 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT07433322, a NA study of Alveolar Bone Loss, is actively recruiting participants, sponsored by Virginia Commonwealth University.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Dental implants are a fixed replacement solution with reported long-term survival rates between 94-98% over 20-40 years. In order to ensure successful implant therapy, adequate bone and soft tissue as well as correct 3D positioning of the implant are required. Upon extraction of a tooth, socket width can decrease by up to 60% within six months post-extraction, with a 11-22% vertical reduction. Additionally, sinus pneumatization occurs post-extraction as the maxillary sinus expands into the empty socket due to disuse atrophy and intra-sinus air pressure, as explained by Wolff's law. This further reduces residual bone height (RBH), often resulting in posterior maxillary sites requiring supplemental procedures to prevent bone loss or to augment the bone height at the time of implant placement. However, if the bone height and width dimensions are sufficient before and after extraction - in that, even with the aforementioned loss in width and height percentages in the latter, a standard implant may still be placed in the surrounding bone, one can argue that grafting may not be necessarily done at the time of extraction. Rather, it can be tailored to the patients' needs; thus potentially reducing overall post-operative discomfort and pain.

Conditions Studied

Interventions

  • OTHER Ossix mineralized grafting immediately at extraction
  • OTHER Delayed grafting at implant placement

Study Locations (1)

Virginia

  • Virginia Commonwealth University - Richmond

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2026-03
Est. Completion 2028-04
Phase NA

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT07433322

The ClinicalTrials.gov registry entry for NCT07433322 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alveolar Bone Loss appearing as the primary indexed condition, and to 2 interventions - of which Ossix mineralized grafting immediately at extraction is the first listed.

NCT07433322 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.

Frequently Asked Questions

What is clinical trial NCT07433322 about?

NCT07433322 is a clinical study titled "Alveolar Ridge Preservation (ARP) in the Posterior Maxilla After the Extraction of Maxillary Molars". Dental implants are a fixed replacement solution with reported long-term survival rates between 94-98% over 20-40 years. In order to ensure successful implant therapy, adequate bone and soft tissue as well as correct 3D positioning of the implant are required. Upon extraction of a tooth, socket widt...

What is the current status of trial NCT07433322?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-03. Estimated completion is 2028-04.

What conditions does trial NCT07433322 study?

This clinical trial studies the following conditions: Alveolar Bone Loss.

What interventions are being tested in trial NCT07433322?

The interventions under investigation include: Ossix mineralized grafting immediately at extraction (OTHER), Delayed grafting at implant placement (OTHER).

Who is sponsoring clinical trial NCT07433322?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07433322 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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