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NCT07350304 · ClinicalTrials.gov registry record
Comparison of Two OCT Device RNFL and GCIPL Measurements in Mild, Moderate, and Severe Glaucoma
A clinical trial, sponsored by Twin Cities Eye Consultants.
- Completed
- Registry status
- 141
- Enrollment target
NCT07350304 is a clinical trial that has completed, run by Twin Cities Eye Consultants. The registered enrollment target is 141 participants.
The verdict
NCT07350304 has completed, sponsored by Twin Cities Eye Consultants.
- COMPLETED
- Registry status
- 141 participants
- Enrollment target
Study Summary
This research study was designed to evaluate how consistently two different imaging devices measure the thickness of retinal layers in patients with glaucoma. The two machines, the Topcon Maestro2 and the Zeiss Cirrus 5000, are commonly used in eye clinics to take high-resolution scans of the retina and optic nerve. These scans help doctors monitor glaucoma and detect disease progression. The goal of this study was to compare the results from both machines when scanning the same patients, and to determine how closely their measurements align. Researchers also developed mathematical models that allow doctors to convert results from one machine to the other, which could help ensure consistency when a patient receives scans on different devices over time or at different clinics. A total of 141 eyes from patients with varying levels of glaucoma severity were included in the study. Scans were performed using standard imaging protocols on both machines. Researchers analyzed the average thickness of two important retinal layers: the retinal nerve fiber layer (RNFL) and the ganglion cell-inner plexiform layer (GCIPL). This study helps improve our understanding of how different imaging devices compare and provides tools for standardizing results across platforms. The findings may help eye care providers make more confident decisions when reviewing images from different machines, improving the care and monitoring of patients with glaucoma. This was an investigator-initiated study sponsored by Twin Cities Eye Consultants with funding support from Topcon Healthcare. No new medications, treatments, or procedures were tested as part of this research. The study only involved non-invasive eye imaging scans that are already widely used in clinical practice.
Interventions
- DIAGNOSTIC_TEST Optical Coherence Tomography
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 141 participants |
| Start Date | 2024-10-28 |
| Est. Completion | 2025-02-14 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07350304
The ClinicalTrials.gov registry entry for NCT07350304 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 141 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Twin Cities Eye Consultants, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Optical Coherence Tomography is the first listed.
NCT07350304 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07350304 about?
NCT07350304 is a clinical study titled "Comparison of Two OCT Device RNFL and GCIPL Measurements in Mild, Moderate, and Severe Glaucoma". This research study was designed to evaluate how consistently two different imaging devices measure the thickness of retinal layers in patients with glaucoma. The two machines, the Topcon Maestro2 and the Zeiss Cirrus 5000, are commonly used in eye clinics to take high-resolution scans of the retina...
What is the current status of trial NCT07350304?
This trial is currently completed. The enrollment target is 141 participants. The study started on 2024-10-28. Estimated completion is 2025-02-14.
What interventions are being tested in trial NCT07350304?
The interventions under investigation include: Optical Coherence Tomography (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07350304?
This trial is sponsored by Twin Cities Eye Consultants, which has 2 total clinical trials registered on ClinicalTrials.gov.
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