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NCT07325188 · ClinicalTrials.gov registry record · NA
HUD Surgical Guidance for Toric Alignment
A NA study of Cataract and IOL Surgery, sponsored by Gainesville Eye Associates.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT07325188: Recruiting NA study of Cataract and IOL Surgery, sponsored by Gainesville Eye Associates.
NCT07325188 is a NA study of Cataract and IOL Surgery that is actively recruiting participants, run by Gainesville Eye Associates. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07325188, a NA study of Cataract and IOL Surgery, is actively recruiting participants, sponsored by Gainesville Eye Associates.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system. In addition, it evaluates the time required to initiate surgical guidance and postoperative refractive astigmatism following toric IOL implantation. This single-surgeon, single-site, prospective, non-invasive observational study evaluated the accuracy of toric IOL alignment axes calculated and displayed by the digital guidance system (Cassini Technologies, B.V.) in 100 eyes. The intraoperatively calculated alignment axes were compared to preoperative measurements to assess their accuracy (in degrees). Postoperative outcomes, including residual refractive astigmatism (diopters) and visual acuity (Snellen), were recorded at 1 month postoperatively.
Primary Outcome
Primary Endpoint: 1\. Accuracy of the calculated alignment axis (degrees of arc = angular degrees) * Definition: The angular difference between the alignment axis for toric IOLs as determined with the CGS and the intended alignment axis as determined with the Cassini Ambient. * Thresholds of interest: ≤3°, ≤5°, ≤10°, \>10°. * Justification: Misalignment greater than 10° results in a clinically significant loss of toric correction (approximately 33%) (Quesada et al., 2022; Hu, 2023), making thi
Conditions Studied
Interventions
- DEVICE Cassini Guidance
Study Locations (1)
Georgia
- North Georgia Eye Associates - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-11-04 |
| Est. Completion | 2026-10-31 |
| Phase | NA |
What NCT07325188 shows while recruiting
NCT07325188 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Cataract and IOL Surgery appearing as the primary indexed condition, and to 1 intervention - of which Cassini Guidance is the first listed.
NCT07325188 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT07325188 about?
NCT07325188 is a clinical study titled "HUD Surgical Guidance for Toric Alignment". This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system. In addition, it evaluates the time required to initiate surgical guidance and postoperative refractive astigmatism following toric IOL implantation. ...
What is the current status of trial NCT07325188?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-11-04. Estimated completion is 2026-10-31.
What conditions does trial NCT07325188 study?
This clinical trial studies the following conditions: Cataract and IOL Surgery.
What interventions are being tested in trial NCT07325188?
The interventions under investigation include: Cassini Guidance (DEVICE).
Who is sponsoring clinical trial NCT07325188?
This trial is sponsored by Gainesville Eye Associates, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07325188 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07325188's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
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Source ClinicalTrials.gov registry export · 2026-08-08
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