Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 1

A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures

NCT07233239 · View on ClinicalTrials.gov ↗

Study Summary

Cannabidiol oral solution (CBD-OS) is approved in the US for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or Tuberous sclerosis complex (TSC) in patients 1 year of age and older. This study will assess the efficacy and safety of CBD-OS in participants aged 12 to 75 years for the treatment of focal-onset seizures (FOS).

Conditions Studied

Interventions

  • DRUG CBD-OS

Study Locations (20)

Georgia

  • Emory University — Atlanta
  • Savannah Neurology Specialists — Savannah

Michigan

  • Wayne State University — Detroit
  • Corewell Health — Grand Rapids

New Jersey

  • Hackensack Meridian Neuroscience Institute at JFK University Medical Center — Edison
  • Saint Peter's University Hospital — New Brunswick

North Carolina

  • Onsite Clinical Solutions — Charlotte
  • Velocity Clinical Research at Raleigh Neurology — Raleigh

Ohio

  • Cincinnati Children's Hospital — Cincinnati
  • University of Cincinnati, Gardner Neuroscience Institute — Cincinnati

Arizona

  • Banner University Medical Center-Phoenix — Phoenix

California

  • UC San Diego — La Jolla

Connecticut

  • Yale University — New Haven

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2025-11-26
Est. Completion 2027-11-29
Phase Phase 1

Sponsor

Jazz Pharmaceuticals

37 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07233239

The ClinicalTrials.gov registry entry for NCT07233239 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jazz Pharmaceuticals, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Focal Seizures appearing as the primary indexed condition, and to 1 intervention — of which CBD-OS is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07233239 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Georgia, Michigan, New Jersey. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07233239 about?

NCT07233239 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures". Cannabidiol oral solution (CBD-OS) is approved in the US for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or Tuberous sclerosis complex (TSC) in patients 1 year of age and older. This study will assess the efficacy and safety of CBD-OS in participant...

What is the current status of trial NCT07233239?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2025-11-26. Estimated completion is 2027-11-29.

What conditions does trial NCT07233239 study?

This clinical trial studies the following conditions: Focal Seizures. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07233239?

The interventions under investigation include: CBD-OS (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07233239?

This trial is sponsored by Jazz Pharmaceuticals, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07233239 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial