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NCT07222826 · ClinicalTrials.gov registry record · NA
Non-invasive Intracranial Pressure Estimation by Measurement of the Occlusion Pressure of the Isolated Periorbital Vein
A NA study of Intracranial Pressure and Intracranial Pressure Changes, sponsored by Compremium.
- Recruiting
- Registry status
- NA
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT07222826 is a NA study of Intracranial Pressure and Intracranial Pressure Changes that is actively recruiting participants, run by Compremium. The registered enrollment target is 15 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07222826, a NA study of Intracranial Pressure and Intracranial Pressure Changes, is actively recruiting participants, sponsored by Compremium.
- RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
Elevated intracranial pressure is a common complication of brain injury which means that the pressure within the skull rises above normal levels. The negative impact of increased intracranial pressure (ICP) on the prognosis of patients has been strongly shown in numerous studies and ICP-based treatment is associated with an important reduction of risk of death. Invasive ICP measurement methods are nowadays a standard of care in severe brain injury. The two available ways of measuring ICP require neurosurgical procedure to implant a catheter and probes within the brain and present risks and complications for the patient, such as infections and intracranial bleeding. In addition, invasive recording of ICP requires neurosurgical expertise and intensive care unit (ICU) facilities, limiting the application of ICP measurements to patients of the acute neuro-ICU (neuro-Intensive Care Unit) with acute brain damage requiring close surveillance to prevent further deterioration of neural tissue and disability. Non-invasive ICP monitoring benefits include no risk of complications seen in invasive monitoring, helping in deciding which patient needs invasive ICP monitoring, and providing ongoing long-term measurements of ICP without having to insert a new device every time. Although many non-invasive ICP measurement methods have been explored, to date, none of them have shown clinical success or usefulness. One under-explored window to ICP is the orbital vein, a small blood vessel located near your eye, which we think could provide a direct link to the intracranial pressure. The study device, called the CPMX3 system, is a non-invasive method to measure pressure in a superficial periorbital vein.
Conditions Studied
Interventions
- DEVICE CPMX3
Study Locations (1)
Texas
- Baylor College of Medicine - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2025-09-30 |
| Est. Completion | 2026-09-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07222826
The ClinicalTrials.gov registry entry for NCT07222826 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Compremium, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Intracranial Pressure appearing as the primary indexed condition, and to 1 intervention - of which CPMX3 is the first listed.
NCT07222826 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT07222826 about?
NCT07222826 is a clinical study titled "Non-invasive Intracranial Pressure Estimation by Measurement of the Occlusion Pressure of the Isolated Periorbital Vein". Elevated intracranial pressure is a common complication of brain injury which means that the pressure within the skull rises above normal levels. The negative impact of increased intracranial pressure (ICP) on the prognosis of patients has been strongly shown in numerous studies and ICP-based treatm...
What is the current status of trial NCT07222826?
This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2025-09-30. Estimated completion is 2026-09-30.
What conditions does trial NCT07222826 study?
This clinical trial studies the following conditions: Intracranial Pressure, Intracranial Pressure Changes.
What interventions are being tested in trial NCT07222826?
The interventions under investigation include: CPMX3 (DEVICE).
Who is sponsoring clinical trial NCT07222826?
This trial is sponsored by Compremium, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07222826 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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