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NCT07212868 · ClinicalTrials.gov registry record · Phase 1
The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery
A Phase 1 study of Non-Diabetic, sponsored by The University of Texas Health Science Center at San Antonio.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 150
- Enrollment target
- 2
- Study locations
NCT07212868 is a Phase 1 study of Non-Diabetic that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 150 participants. The trial reports 2 study locations across 1 state.
The verdict
NCT07212868, a Phase 1 study of Non-Diabetic, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 150 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this study is to understand the role of glucagon signal on glucose metabolism in individuals with and without bariatric surgery. The study is involved with measuring glucose metabolism with glucagon infusion and glucagon receptor blockade. We use an investigational drug called REMD 477. "Investigational" means that the has not yet been approved by the U.S. Food \& Drug Administration (FDA). REMD-477 is a monoclonal antibody (an antibody made by cloning a unique white blood cell) that blocks the effect of glucagon.
Conditions Studied
Interventions
- DRUG REMD-477 versus Placebo
- OTHER Exogenous glucagon versus saline infusion
Study Locations (2)
Texas
- Texas Diabetes Institute - University Health System - San Antonio
- University of Texas San Antonio - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2026-02-25 |
| Est. Completion | 2030-06-30 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07212868
The ClinicalTrials.gov registry entry for NCT07212868 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The University of Texas Health Science Center at San Antonio, which has 378 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Non-Diabetic appearing as the primary indexed condition, and to 2 interventions - of which REMD-477 versus Placebo is the first listed.
NCT07212868 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT07212868 about?
NCT07212868 is a clinical study titled "The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery". The goal of this study is to understand the role of glucagon signal on glucose metabolism in individuals with and without bariatric surgery. The study is involved with measuring glucose metabolism with glucagon infusion and glucagon receptor blockade. We use an investigational drug called REMD 477. ...
What is the current status of trial NCT07212868?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 150 participants. The study started on 2026-02-25. Estimated completion is 2030-06-30.
What conditions does trial NCT07212868 study?
This clinical trial studies the following conditions: Non-Diabetic.
What interventions are being tested in trial NCT07212868?
The interventions under investigation include: REMD-477 versus Placebo (DRUG), Exogenous glucagon versus saline infusion (OTHER).
Who is sponsoring clinical trial NCT07212868?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07212868 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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