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NCT07199829 · ClinicalTrials.gov registry record · NA

Evaluating Response to Vitamin D3 and K2 Supplementation in Healthcare Personnel

A NA study of Hypovitaminosis D and Hypovitaminosis, sponsored by Madigan Army Medical Center.

Recruiting
Registry status
NA
Development phase
96
Enrollment target
1
Study location

NCT07199829: Recruiting NA study of Hypovitaminosis D and Hypovitaminosis, sponsored by Madigan Army Medical Center.

NCT07199829 is a NA study of Hypovitaminosis D and Hypovitaminosis that is actively recruiting participants, run by Madigan Army Medical Center. The registered enrollment target is 96 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07199829, a NA study of Hypovitaminosis D and Hypovitaminosis, is actively recruiting participants, sponsored by Madigan Army Medical Center.

RECRUITING
Registry status
NA
Development phase
96 participants
Enrollment target
1
Study location

Study Summary

The main purpose of this research study is to learn about the effects of supplemental vitamin D3 and vitamin K2 on blood levels and the gut microbial community, called the gut microbiome. There are many influences on blood levels of vitamin D and K to include your dietary intake, lifestyle behaviors (physical activity, sleep), genetic alterations in metabolism of these vitamins, and the gut microbial abundance and diversity. You will be asked to take one capsule containing vitamin D3 (125 mcg), vitamin K2 (180 mcg), a combination of vitamins D3 and K2 (same doses as previous), or a placebo powder for 90 days. You will also be asked to complete questionnaires, undergo body composition and blood pressure measurements, provide blood samples and a stool swab, all on 2 occasions about 3 - 4 months apart. By conducting this study, we aim to identify the frequency of common genetic alterations in vitamins D and K metabolism and establish the impact on the gut microbiome for the first time. Your participation in this study will last about 4 - 6 months and include up to 3 visits.

Primary Outcome

Evaluate effect of vitamin D3 and K2 dietary intake, and assigned vitamin supplementation group versus placebo group, on the gut microbiome composition

Interventions

  • OTHER Placebo
  • DIETARY_SUPPLEMENT Vitamin Arm 1
  • DIETARY_SUPPLEMENT Vitamin Arm 2
  • DIETARY_SUPPLEMENT Vitamin Arm 3

Study Locations (1)

Washington

  • Madigan Army Medical Center - Tacoma

Trial Details

FieldValue
Enrollment Target 96 participants
Start Date 2025-03-27
Est. Completion 2026-03
Phase NA
Madigan Army Medical Center

22 total trials

What NCT07199829 shows while recruiting

NCT07199829 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 96 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 2 conditions, with Hypovitaminosis D appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT07199829 reports a single indexed study location in Washington.

Frequently Asked Questions

What is clinical trial NCT07199829 about?

NCT07199829 is a clinical study titled "Evaluating Response to Vitamin D3 and K2 Supplementation in Healthcare Personnel". The main purpose of this research study is to learn about the effects of supplemental vitamin D3 and vitamin K2 on blood levels and the gut microbial community, called the gut microbiome. There are many influences on blood levels of vitamin D and K to include your dietary intake, lifestyle behaviors...

What is the current status of trial NCT07199829?

This trial is currently recruiting. It is a NA study. The enrollment target is 96 participants. The study started on 2025-03-27. Estimated completion is 2026-03.

What conditions does trial NCT07199829 study?

This clinical trial studies the following conditions: Hypovitaminosis D, Hypovitaminosis.

What interventions are being tested in trial NCT07199829?

The interventions under investigation include: Placebo (OTHER), Vitamin Arm 1 (DIETARY_SUPPLEMENT), Vitamin Arm 2 (DIETARY_SUPPLEMENT), Vitamin Arm 3 (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT07199829?

This trial is sponsored by Madigan Army Medical Center, which has 22 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07199829 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hypovitaminosis D

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07199829's enrollment target sits among peer trials

96 925th of 2000 higher than 1,070 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07199829, the US trial registry maintained by the National Library of Medicine. NCT07199829 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.