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NCT07178704 · ClinicalTrials.gov registry record
The Metabolic and Genetic Drivers of Body Composition Changes Following Weight Loss Surgery
A clinical trial of Bariatric Surgery Patients, sponsored by The University of Texas Medical Branch, Galveston.
- Recruiting
- Registry status
- 110
- Enrollment target
- 1
- Study location
NCT07178704 is a study of Bariatric Surgery Patients that is actively recruiting participants, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 110 participants, roughly in line with the 107-participant average among 3 other Bariatric Surgery Patients trials with a reported enrollment target. The trial reports 1 study location across 1 state.
The verdict
NCT07178704, a study of Bariatric Surgery Patients, is actively recruiting participants, sponsored by The University of Texas Medical Branch, Galveston.
- RECRUITING
- Registry status
- 110 participants
- Enrollment target
- 1
- Study location
Study Summary
Weight loss surgery is very good at reducing body weight but it can also cause the loss of both muscle and strength. Some patients undergoing weight loss surgery do not achieve their weight loss goals and regain the weight they lost. When this occurs, the loss of muscle and strength combined with the regain of weight can impact the individual's quality of life and ability to remain active and mobile. The purpose of this study is to understand the behavioral, biological, and genetic factors that influence the success of weight loss surgery and its impact on muscle mass. Bariatric surgery patients participating in the trial will be monitored prior to, and for a year following weight loss surgery, with data collected about their eating habits, hand grip strength, and the loss of fat, muscle, and body weight following surgery. Some patients will be additionally invited to undergo detailed metabolic assessment, where we will measure how their body uses nutrients it consumes, the composition of their body (e.g. how much lean and fat tissue they have and where it is stored), identify the bacteria living in their gut, and determine their physical performance. In all patients a small sample of gut tissue will be collected at a routine endoscopy performed in advance of weight loss surgery to identify the expression (activity) of genes in their DNA. Healthy subjects will also be recruited to allow us to compare between healthy weight individuals and those undergoing weight loss surgery. On a single occasion, the healthy volunteers will undergo the same detailed metabolic assessment performed in patients as described above. We will not examine the bacteria living in the gut of the healthy volunteers, nor will we collect gut tissue from these individuals.
Conditions Studied
Study Locations (1)
Texas
- The University of Texas Medical Branch - Galveston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2025-11-04 |
| Est. Completion | 2027-08 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07178704
The ClinicalTrials.gov registry entry for NCT07178704 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 107-participant average among 3 other Bariatric Surgery Patients trials with a reported enrollment target. The listed sponsor is The University of Texas Medical Branch, Galveston, which has 203 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Bariatric Surgery Patients appearing as the primary indexed condition, and to 0 interventions.
NCT07178704 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT07178704 about?
NCT07178704 is a clinical study titled "The Metabolic and Genetic Drivers of Body Composition Changes Following Weight Loss Surgery". Weight loss surgery is very good at reducing body weight but it can also cause the loss of both muscle and strength. Some patients undergoing weight loss surgery do not achieve their weight loss goals and regain the weight they lost. When this occurs, the loss of muscle and strength combined with th...
What is the current status of trial NCT07178704?
This trial is currently recruiting. The enrollment target is 110 participants. The study started on 2025-11-04. Estimated completion is 2027-08.
What conditions does trial NCT07178704 study?
This clinical trial studies the following conditions: Bariatric Surgery Patients.
Who is sponsoring clinical trial NCT07178704?
This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07178704 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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