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NCT07152249 · ClinicalTrials.gov registry record · NA
Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial
A NA study of Postoperative Nausea and Postoperative Vomiting, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 19,480
- Enrollment target
- 1
- Study location
NCT07152249 is a NA study of Postoperative Nausea and Postoperative Vomiting that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 19,480 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07152249, a NA study of Postoperative Nausea and Postoperative Vomiting, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 19,480 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this prospective, unblinded, pragmatic and repeated crossover trial is to learn if clinical decision support alerts will impact postoperative nausea and vomiting (PONV) prophylaxis and reduce PONV rates in adult patients who have planned surgery with general anesthesia. The main aim is to improve PONV, establishing a scalable Clinical Decision Support (CDS) Tool for personalized PONV prevention. The primary hypothesis is that, compared with standard care, the Anesthesia Workflow-Driven Clinical Decision Support Tool for Personalized PONV Prevention will be associated with a significant improvement in the rate of appropriate administration of PONV prophylaxis and a significant decrease in the incidence of PONV. This study will evaluate a new clinical decision support (CDS) tool designed to improve how and when PONV prevention strategies are used. Unlike traditional tools that provide generic, one-time alerts, this new system is integrated into the electronic health record (EHR) and delivers timely, targeted reminders to anesthesia providers at key moments during a patient's surgical care-such as before surgery begins, after anesthesia is given, and before the patient wakes up. These alerts are based on each patient's individual risk for PONV and are intended to support, not replace, clinical judgment. The study will use a crossover design over 12 months, alternating between periods when the tool is active and when it is not. The goal is to determine whether this time-sensitive, workflow-integrated tool can lead to better adherence to best practices and improved patient outcomes.
Conditions Studied
Interventions
- OTHER AW-D Clinical Decision Support Tool
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19,480 participants |
| Start Date | 2025-09-03 |
| Est. Completion | 2026-09 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07152249
The ClinicalTrials.gov registry entry for NCT07152249 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 19,480 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Postoperative Nausea appearing as the primary indexed condition, and to 1 intervention - of which AW-D Clinical Decision Support Tool is the first listed.
NCT07152249 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT07152249 about?
NCT07152249 is a clinical study titled "Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial". The goal of this prospective, unblinded, pragmatic and repeated crossover trial is to learn if clinical decision support alerts will impact postoperative nausea and vomiting (PONV) prophylaxis and reduce PONV rates in adult patients who have planned surgery with general anesthesia. The main aim is t...
What is the current status of trial NCT07152249?
This trial is currently recruiting. It is a NA study. The enrollment target is 19,480 participants. The study started on 2025-09-03. Estimated completion is 2026-09.
What conditions does trial NCT07152249 study?
This clinical trial studies the following conditions: Postoperative Nausea, Postoperative Vomiting.
What interventions are being tested in trial NCT07152249?
The interventions under investigation include: AW-D Clinical Decision Support Tool (OTHER).
Who is sponsoring clinical trial NCT07152249?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07152249 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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