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NCT07136623 · ClinicalTrials.gov registry record

Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope

A clinical trial of Pulmnary Hypertension, sponsored by Eko Devices.

Recruiting
Registry status
1,513
Enrollment target
2
Study locations

NCT07136623 is a study of Pulmnary Hypertension that is actively recruiting participants, run by Eko Devices. The registered enrollment target is 1,513 participants. The trial reports 2 study locations across 2 states.

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The verdict

NCT07136623, a study of Pulmnary Hypertension, is actively recruiting participants, sponsored by Eko Devices.

RECRUITING
Registry status
1,513 participants
Enrollment target
2
Study locations

Study Summary

This prospective, observational study will evaluate whether synchronized heart sound (phonocardiogram, PCG) and three-lead electrocardiogram (ECG) recordings (entered as separate interventions in PRS, though collected together in practice) collected with the Eko CORE 500 can help screen for pulmonary hypertension (PH). Adults (≥18 years) undergoing clinically indicated transthoracic echocardiography (TTE) and/or right heart catheterization (RHC) will complete one study visit (\~20 minutes). During the visit, study staff will obtain at least four 15-second CORE 500 recordings (aortic, pulmonic, tricuspid, and mitral areas). The clinical echocardiogram (and RHC, if performed) within ±7 days of the recordings will provide reference labels for the presence and severity of PH; de-identified demographic and clinical data may also be abstracted from the medical record. The primary objective is to develop and validate a software algorithm to detect PH and, where possible, stratify severity using noninvasive PCG+ECG signals. These recordings are investigational data acquisitions for algorithm development only; they are not diagnostic procedures and will not be used for clinical decision-making. Primary performance measures are sensitivity and specificity versus echocardiogram and RHC references. No clinical decisions will be based on the investigational algorithm, and no changes to standard care are required. The study plans to enroll up to \~1,513 participants to obtain approximately 1,375 evaluable datasets across multiple outpatient sites.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST Eko CORE 500 phonocardiogram (PCG) recording
  • DIAGNOSTIC_TEST Eko CORE 500 three-lead electrocardiogram (ECG) recording

Study Locations (2)

California

  • University of California Los Angeles - Los Angeles

North Carolina

  • Duke University - Durham

Trial Details

FieldValue
Enrollment Target 1,513 participants
Start Date 2025-08-01
Est. Completion 2026-08-01

Sponsor

Eko Devices

16 total trials

What the Registry Record Tells You About NCT07136623

The ClinicalTrials.gov registry entry for NCT07136623 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,513 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eko Devices, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pulmnary Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Eko CORE 500 phonocardiogram (PCG) recording is the first listed.

NCT07136623 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, North Carolina.

Frequently Asked Questions

What is clinical trial NCT07136623 about?

NCT07136623 is a clinical study titled "Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope". This prospective, observational study will evaluate whether synchronized heart sound (phonocardiogram, PCG) and three-lead electrocardiogram (ECG) recordings (entered as separate interventions in PRS, though collected together in practice) collected with the Eko CORE 500 can help screen for pulmonar...

What is the current status of trial NCT07136623?

This trial is currently recruiting. The enrollment target is 1,513 participants. The study started on 2025-08-01. Estimated completion is 2026-08-01.

What conditions does trial NCT07136623 study?

This clinical trial studies the following conditions: Pulmnary Hypertension.

What interventions are being tested in trial NCT07136623?

The interventions under investigation include: Eko CORE 500 phonocardiogram (PCG) recording (DIAGNOSTIC_TEST), Eko CORE 500 three-lead electrocardiogram (ECG) recording (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT07136623?

This trial is sponsored by Eko Devices, which has 16 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07136623 being conducted?

This trial has 2 study locations across California, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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