Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07120386 · ClinicalTrials.gov registry record · NA
Irrigating vs Traditional Negative Pressure Wound Therapy to Treat Necrotizing Soft Tissue Infections
A NA study of Necrotizing Soft Tissue Infections, sponsored by HealthPartners Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07120386: Recruiting NA study of Necrotizing Soft Tissue Infections, sponsored by HealthPartners Institute.
NCT07120386 is a NA study of Necrotizing Soft Tissue Infections that is actively recruiting participants, run by HealthPartners Institute. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07120386, a NA study of Necrotizing Soft Tissue Infections, is actively recruiting participants, sponsored by HealthPartners Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Necrotizing Soft Tissue Infections (NSTIs) are rapidly progressing infections that have a high morbidity and mortality, with the greatest morbidity related to managing the large wounds required to treat these patients. Initial treatment requires wide surgical removal of infected tissue and optimal management is essential to reducing morbidity in these patients. Negative pressure wound therapy (NPWT) is a widely used technology that has revolutionized wound management. NPWT is utilized across the spectrum of acute wounds, including routine postoperative incision management, traumatic wounds, and wounds related to surgical debridement of NSTIs which are frequently some of the most complicated of wounds encountered. Most NSTI cases at Regions Hospital currently utilize negative pressure wound therapy with instillation (NPWTi) where the wound is irrigated to clean out debris. Currently, there is a paucity of data comparing traditional NPWT and NPWTi and the choice of which device to use is left to surgeon discretion. This study is a first step at identifying the effects of NPWTi compared to NPWT alone on the care of NSTI patients. If the theoretical benefits of NPWTi over NPWT translate to practice, those treated with NPWTi would be expected to have a reduced rate of hospital readmission after their index hospitalization in addition to shorter time to definitive closure/coverage. This is a pilot study to assess the feasibility of enrolling patients with NSTIs in a randomized controlled trial to assess outcomes between the two devices.
Conditions Studied
Interventions
- DEVICE Negative Pressure Wound Therapy
- DEVICE Negative Pressure Wound Therapy with Instillation
Study Locations (1)
Minnesota
- Regions Hospital - Saint Paul
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-08-01 |
| Est. Completion | 2026-10 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07120386
The ClinicalTrials.gov registry entry for NCT07120386 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The listed sponsor is HealthPartners Institute, which has 146 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Necrotizing Soft Tissue Infections appearing as the primary indexed condition, and to 2 interventions - of which Negative Pressure Wound Therapy is the first listed.
NCT07120386 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT07120386 about?
NCT07120386 is a clinical study titled "Irrigating vs Traditional Negative Pressure Wound Therapy to Treat Necrotizing Soft Tissue Infections". Necrotizing Soft Tissue Infections (NSTIs) are rapidly progressing infections that have a high morbidity and mortality, with the greatest morbidity related to managing the large wounds required to treat these patients. Initial treatment requires wide surgical removal of infected tissue and optimal m...
What is the current status of trial NCT07120386?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-08-01. Estimated completion is 2026-10.
What conditions does trial NCT07120386 study?
This clinical trial studies the following conditions: Necrotizing Soft Tissue Infections.
What interventions are being tested in trial NCT07120386?
The interventions under investigation include: Negative Pressure Wound Therapy (DEVICE), Negative Pressure Wound Therapy with Instillation (DEVICE).
Who is sponsoring clinical trial NCT07120386?
This trial is sponsored by HealthPartners Institute, which has 146 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07120386 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.