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NCT07119398 · ClinicalTrials.gov registry record · Phase 4
Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM
A Phase 4 study of Preterm PROM (Pregnancy), sponsored by Eastern Virginia Medical School.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT07119398: Recruiting Phase 4 study of Preterm PROM (Pregnancy), sponsored by Eastern Virginia Medical School.
NCT07119398 is a Phase 4 study of Preterm PROM (Pregnancy) that is actively recruiting participants, run by Eastern Virginia Medical School. The registered enrollment target is 80 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07119398, a Phase 4 study of Preterm PROM (Pregnancy), is actively recruiting participants, sponsored by Eastern Virginia Medical School.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
Data on the optimal mode of labor induction after preterm prelabor rupture of membranes (PPROM) is lacking. Studies have shown no difference between oxytocin and misoprostol use for labor induction in this cohort (1). The preponderance of evidence from term pregnancies suggests that Foley catheter coupled with oxytocin is better than oxytocin alone, with a higher rate of delivery within 24 hours when a Foley catheter followed by oxytocin is compared to oxytocin alone. However, the use of a Foley catheter has not been evaluated in prospective studies on patients with PPROM.
Primary Outcome
Vaginal Delivery within 12 hours of induction
Conditions Studied
Interventions
- COMBINATION_PRODUCT Oxytocin plus Foley Catheter
- DRUG Oxytocin
Study Locations (1)
Virginia
- Sentara Norfolk General Hospital - Norfolk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-07-14 |
| Est. Completion | 2026-12-30 |
| Phase | Phase 4 |
What NCT07119398 shows while recruiting
NCT07119398 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Preterm PROM (Pregnancy) appearing as the primary indexed condition, and to 2 interventions - of which Oxytocin plus Foley Catheter is the first listed.
NCT07119398 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT07119398 about?
NCT07119398 is a clinical study titled "Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM". Data on the optimal mode of labor induction after preterm prelabor rupture of membranes (PPROM) is lacking. Studies have shown no difference between oxytocin and misoprostol use for labor induction in this cohort (1). The preponderance of evidence from term pregnancies suggests that Foley catheter c...
What is the current status of trial NCT07119398?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2025-07-14. Estimated completion is 2026-12-30.
What conditions does trial NCT07119398 study?
This clinical trial studies the following conditions: Preterm PROM (Pregnancy).
What interventions are being tested in trial NCT07119398?
The interventions under investigation include: Oxytocin plus Foley Catheter (COMBINATION_PRODUCT), Oxytocin (DRUG).
Who is sponsoring clinical trial NCT07119398?
This trial is sponsored by Eastern Virginia Medical School, which has 36 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07119398 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Preterm PROM (Pregnancy)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07119398's enrollment target sits among peer trials
80 946th of 2000 higher than 1,022 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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