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NCT07116876 · ClinicalTrials.gov registry record · NA
Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers
A NA study of Diabetic Foot Ulcer (DFU) and Lower Extremity, sponsored by LifeNet Health.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 18
- Study locations
NCT07116876: Recruiting NA study of Diabetic Foot Ulcer (DFU) and Lower Extremity, sponsored by LifeNet Health.
NCT07116876 is a NA study of Diabetic Foot Ulcer (DFU) and Lower Extremity that is actively recruiting participants, run by LifeNet Health. The registered enrollment target is 120 participants, below the 509-participant average among 13 other Diabetic Foot Ulcer (DFU) trials with a reported enrollment target (76% lower). The trial reports 18 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07116876, a NA study of Diabetic Foot Ulcer (DFU) and Lower Extremity, is actively recruiting participants, sponsored by LifeNet Health.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 18
- Study locations
Study Summary
This study will evaluate Matrion™ (LifeNet Health, Inc., Virginia Beach, VA), a placental membrane product, as a treatment for diabetic foot ulcers compared to conventional wound care. Matrion is derived from donated human birth tissue and includes both the amniotic and chorionic layers, along with the trophoblast layer. It is minimally processed using a proprietary decellularization method and terminally sterilized to ensure the membrane is acellular and sterile, making it suitable for surgical applications.
Primary Outcome
Proportion of diabetic foot ulcers that have achieved complete wound closure
Conditions Studied
Interventions
- OTHER Graft Application
- OTHER Wound Dressing Material
Study Locations (18)
California
- Bay Area Foot Care - Castro Valley
- Limb Preservaion Platform, Inc. - Fresno
- Center for Clinical Research, Inc - San Francisco
- Bay Area Foot Care - San Francisco
- ILD Research Center - Vista
Florida
- Humanity Clinical Research, Corp - Aventura
- South Florida Podiatry - Deerfield Beach
- Dinamo Research & Diagnostic Center, LLC - Hialeah
- Doctors Research Network, Inc. - Miami
Texas
- Olympus Clinical Research - Katy
- Element Research Group - San Antonio
- Olympus-Alcanza - Sugar Land
Illinois
- Independent Clinical Research - Decatur
- Independent Clinical Research, LLC - Springfield
North Carolina
- US Foot and Ankle Specialists - Raleigh
- Foot and Ankle Institute of the Carolinas - Rocky Mount
Arizona
- Compass Medical Research Center - Tucson
Virginia
- Foot and Ankle Specialists of the Mid-Atlantic - Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-06-26 |
| Est. Completion | 2026-06 |
| Phase | NA |
What NCT07116876 shows while recruiting
NCT07116876 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 509-participant average among 13 other Diabetic Foot Ulcer (DFU) trials with a reported enrollment target (76% lower).
The record links to 2 conditions, with Diabetic Foot Ulcer (DFU) appearing as the primary indexed condition, and to 2 interventions - of which Graft Application is the first listed.
NCT07116876 lists 18 locations in 7 states (California, Florida, Texas).
Frequently Asked Questions
What is clinical trial NCT07116876 about?
NCT07116876 is a clinical study titled "Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers". This study will evaluate Matrion™ (LifeNet Health, Inc., Virginia Beach, VA), a placental membrane product, as a treatment for diabetic foot ulcers compared to conventional wound care. Matrion is derived from donated human birth tissue and includes both the amniotic and chorionic layers, along with ...
What is the current status of trial NCT07116876?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-06-26. Estimated completion is 2026-06.
What conditions does trial NCT07116876 study?
This clinical trial studies the following conditions: Diabetic Foot Ulcer (DFU), Lower Extremity.
What interventions are being tested in trial NCT07116876?
The interventions under investigation include: Graft Application (OTHER), Wound Dressing Material (OTHER).
Who is sponsoring clinical trial NCT07116876?
This trial is sponsored by LifeNet Health, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07116876 being conducted?
This trial has 18 study locations across Arizona, California, Florida, Illinois, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetic Foot Ulcer (DFU)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07116876's enrollment target sits among peer trials
120 11th of 13 higher than 3 of 13 other Diabetic Foot Ulcer (DFU) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetic Foot Ulcer (DFU) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers
RECRUITING · NA
-
CARE-D-FOOT-Nav Pilot
RECRUITING · NA
-
A Prospective Clinical Study to Evaluate the Effectiveness and Safety of Xcell Amnio MatrixTM (XAM) in the Management of Chronic Non-healing DFUs
RECRUITING · NA
-
CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations
RECRUITING · NA
-
Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs
RECRUITING · NA
-
Remote Temperature and Visual Monitoring To Help Manage Diabetic Foot Ulcers
ACTIVE NOT RECRUITING · NA
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