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NCT07115563 · ClinicalTrials.gov registry record · NA

Daily Amino Acid Supplementation for People With Parkinson's Disease

A NA study of Parkinson Disease (PD), sponsored by Cristina Colon-Semenza.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT07115563: Recruiting NA study of Parkinson Disease (PD), sponsored by Cristina Colon-Semenza.

NCT07115563 is a NA study of Parkinson Disease (PD) that is actively recruiting participants, run by Cristina Colon-Semenza. The registered enrollment target is 30 participants, roughly in line with the 32-participant average among 3 other Parkinson Disease (PD) trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07115563, a NA study of Parkinson Disease (PD), is actively recruiting participants, sponsored by Cristina Colon-Semenza.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn if a tailored amino acid supplement works to help adults living with Parkinson's disease to improve nutrition, metabolic function, body composition, and physical and mental function. The main questions it aims to answer are: Does the tailored amino acid supplement increase essential amino acids (nutritional status)? Does the tailored amino acid supplement increase an antioxidant (complex amino acid) and decrease an amino acid associated with oxidative stress? Does the tailored amino acid supplement improve physical and mental health compared to a placebo supplement? Researchers will compare the tailored amino acid supplement to a placebo (a look-alike substance that contains no active ingredients) to see if the tailored amino acid supplements work to support health for people with Parkinson's disease. Participants will: Take the tailored amino acid supplement or a placebo every day for 6 months, visit the lab at baseline, after 3 months, and after 6 months for fasting blood draws, body composition assessment, and physical and mental health testing and keep a diary of their food intake and supplement intake.

Primary Outcome

Circulating amino acid concentrations will be measured from blood samples using high performance liquid chromatography using a solid phase column specifically designed to test amino acids (e.g. 00F-4435-E0, Phenomenex, USA) along with appropriate column guards (e.g. AJ0-7597 \& KJ0-4282, Phenomenex, USA) and liquid phases. This analysis will be performed at the Laboratory of Mass Spectroscopy and Omics Analysis.

Conditions Studied

Interventions

  • DIETARY_SUPPLEMENT Control (placebo)
  • DIETARY_SUPPLEMENT Targeted Amino Acid Supplement

Study Locations (1)

Connecticut

  • University of Connecticut - Storrs

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-10-31
Est. Completion 2027-11
Phase NA
Cristina Colon-Semenza

1 total trials

What NCT07115563 shows while recruiting

NCT07115563 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, roughly in line with the 32-participant average among 3 other Parkinson Disease (PD) trials with a reported enrollment target.

The record links to 1 condition, with Parkinson Disease (PD) appearing as the primary indexed condition, and to 2 interventions - of which Control (placebo) is the first listed.

NCT07115563 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT07115563 about?

NCT07115563 is a clinical study titled "Daily Amino Acid Supplementation for People With Parkinson's Disease". The goal of this clinical trial is to learn if a tailored amino acid supplement works to help adults living with Parkinson's disease to improve nutrition, metabolic function, body composition, and physical and mental function. The main questions it aims to answer are: Does the tailored amino acid s...

What is the current status of trial NCT07115563?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-10-31. Estimated completion is 2027-11.

What conditions does trial NCT07115563 study?

This clinical trial studies the following conditions: Parkinson Disease (PD).

What interventions are being tested in trial NCT07115563?

The interventions under investigation include: Control (placebo) (DIETARY_SUPPLEMENT), Targeted Amino Acid Supplement (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT07115563?

This trial is sponsored by Cristina Colon-Semenza, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07115563 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT07115563, the US trial registry maintained by the National Library of Medicine. NCT07115563 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.