Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07088510 · ClinicalTrials.gov registry record · NA

Hysteroscopic Resection Versus Manual Vacuum Aspiration for Early Pregnancy

A NA study of Miscarriage in First Trimester, sponsored by University Hospitals Cleveland Medical Center.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT07088510: Recruiting NA study of Miscarriage in First Trimester, sponsored by University Hospitals Cleveland Medical Center.

NCT07088510 is a NA study of Miscarriage in First Trimester that is actively recruiting participants, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07088510, a NA study of Miscarriage in First Trimester, is actively recruiting participants, sponsored by University Hospitals Cleveland Medical Center.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

Early pregnancy loss happens when a pregnancy that is not developing properly is found on an ultrasound before 12 weeks and 6 days. This type of loss occurs in about 10% of pregnancies. There are three main ways to treat this: waiting for it to pass naturally, using medication, or having surgery. Surgery is the most effective, working 99% of the time, compared to waiting (80% effective in 8 weeks) and medication (71-84% effective). Currently, surgery involves dilation of the cervix and curettage (removal of pregnancy tissue) with suction provided either from a manual hand-held pump or a machine. For the purposes of this study, a manual vacuum aspirator (or hand-held pump) will be used with ultrasound guidance. There is also another method called hysteroscopic resection, where the doctor uses a special camera to directly see and remove any pregnancy tissue from your uterus. Patients often want the quickest way to resolve the pregnancy loss, and physicians are unsure which surgical method is the best. It's also unclear if one type of surgery causes less scar tissue inside the uterus, affects the ability to test the tissue for genetic issues, or impacts how soon a patient can start fertility treatments again. This study aims to find out if hysteroscopic resection provides faster resolution and creates less scar tissue compared to the manual vacuum aspiration.

Interventions

  • PROCEDURE Hysteroscopic resection
  • PROCEDURE Manual Vacuum Aspiration

Study Locations (1)

Ohio

  • University Hospitals - Cleveland

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2025-03-31
Est. Completion 2028-04-30
Phase NA

What NCT07088510 shows while recruiting

NCT07088510 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 1 condition, with Miscarriage in First Trimester appearing as the primary indexed condition, and to 2 interventions - of which Hysteroscopic resection is the first listed.

NCT07088510 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT07088510 about?

NCT07088510 is a clinical study titled "Hysteroscopic Resection Versus Manual Vacuum Aspiration for Early Pregnancy". Early pregnancy loss happens when a pregnancy that is not developing properly is found on an ultrasound before 12 weeks and 6 days. This type of loss occurs in about 10% of pregnancies. There are three main ways to treat this: waiting for it to pass naturally, using medication, or having surgery. Su...

What is the current status of trial NCT07088510?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2025-03-31. Estimated completion is 2028-04-30.

What conditions does trial NCT07088510 study?

This clinical trial studies the following conditions: Miscarriage in First Trimester.

What interventions are being tested in trial NCT07088510?

The interventions under investigation include: Hysteroscopic resection (PROCEDURE), Manual Vacuum Aspiration (PROCEDURE).

Who is sponsoring clinical trial NCT07088510?

This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07088510 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Miscarriage in First Trimester

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07088510's enrollment target sits among peer trials

80 994th of 2000 higher than 941 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01243931 · 80 participants · NA

    Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

  • NCT01659203 · 80 participants · Phase 1

    Proton or Photon RT for Retroperitoneal Sarcomas

  • NCT01803451 · 80 participants · Early Phase 1

    Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

  • NCT01964859 · 80 participants · Phase 2

    Feasibility Study for Fibroblast Autologous Skin Grafts

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT07088510, the US trial registry maintained by the National Library of Medicine. NCT07088510 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.