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NCT07081087 · ClinicalTrials.gov registry record

Development of a Peripheral Blood Assay to Replace BM Evaluation in Cytopenia - a Multi-Center Observational Study

A clinical trial of Cytopenia, sponsored by Weizmann Institute of Science.

Recruiting
Registry status
1,500
Enrollment target
2
Study locations

NCT07081087 is a study of Cytopenia that is actively recruiting participants, run by Weizmann Institute of Science. The registered enrollment target is 1,500 participants, above the 243-participant average among 11 other Cytopenia trials with a reported enrollment target (517% higher). The trial reports 2 study locations across 2 states.

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The verdict

NCT07081087, a study of Cytopenia, is actively recruiting participants, sponsored by Weizmann Institute of Science.

RECRUITING
Registry status
1,500 participants
Enrollment target
2
Study locations

Study Summary

This study aims to validate a novel, non-invasive diagnostic approach for blood and bone marrow malignancies using single-cell RNA sequencing of circulating hematopoietic stem and progenitor cells (cHSPCs) from peripheral blood. Building on prior work defining normal cHSPC profiles in healthy individuals, the study introduces a pipeline for identifying blood pathologies, with a focus on improving the diagnosis and subclassification of myelodysplastic syndromes (MDS). A multi-center clinical trial is proposed to evaluate the method's ability to predict bone marrow results in patients with cytopenia, potentially reducing reliance on bone marrow biopsies.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST PERIBLOOD

Study Locations (2)

California

  • University of California San Diego - San Diego

Florida

  • University of Miami - Miami

Trial Details

FieldValue
Enrollment Target 1,500 participants
Start Date 2025-06-01
Est. Completion 2028-12

Sponsor

Weizmann Institute of Science

1 total trials

What the Registry Record Tells You About NCT07081087

The ClinicalTrials.gov registry entry for NCT07081087 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 243-participant average among 11 other Cytopenia trials with a reported enrollment target (517% higher). The listed sponsor is Weizmann Institute of Science, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cytopenia appearing as the primary indexed condition, and to 1 intervention - of which PERIBLOOD is the first listed.

NCT07081087 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Florida.

Frequently Asked Questions

What is clinical trial NCT07081087 about?

NCT07081087 is a clinical study titled "Development of a Peripheral Blood Assay to Replace BM Evaluation in Cytopenia - a Multi-Center Observational Study". This study aims to validate a novel, non-invasive diagnostic approach for blood and bone marrow malignancies using single-cell RNA sequencing of circulating hematopoietic stem and progenitor cells (cHSPCs) from peripheral blood. Building on prior work defining normal cHSPC profiles in healthy indivi...

What is the current status of trial NCT07081087?

This trial is currently recruiting. The enrollment target is 1,500 participants. The study started on 2025-06-01. Estimated completion is 2028-12.

What conditions does trial NCT07081087 study?

This clinical trial studies the following conditions: Cytopenia.

What interventions are being tested in trial NCT07081087?

The interventions under investigation include: PERIBLOOD (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT07081087?

This trial is sponsored by Weizmann Institute of Science, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07081087 being conducted?

This trial has 2 study locations across California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.