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NCT07081087 · ClinicalTrials.gov registry record
Development of a Peripheral Blood Assay to Replace BM Evaluation in Cytopenia - a Multi-Center Observational Study
A clinical trial of Cytopenia, sponsored by Weizmann Institute of Science.
- Recruiting
- Registry status
- 1,500
- Enrollment target
- 2
- Study locations
NCT07081087: Recruiting study of Cytopenia, sponsored by Weizmann Institute of Science.
NCT07081087 is a study of Cytopenia that is actively recruiting participants, run by Weizmann Institute of Science. The registered enrollment target is 1,500 participants, above the 243-participant average among 11 other Cytopenia trials with a reported enrollment target (517% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07081087, a study of Cytopenia, is actively recruiting participants, sponsored by Weizmann Institute of Science.
- RECRUITING
- Registry status
- 1,500 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study aims to validate a novel, non-invasive diagnostic approach for blood and bone marrow malignancies using single-cell RNA sequencing of circulating hematopoietic stem and progenitor cells (cHSPCs) from peripheral blood. Building on prior work defining normal cHSPC profiles in healthy individuals, the study introduces a pipeline for identifying blood pathologies, with a focus on improving the diagnosis and subclassification of myelodysplastic syndromes (MDS). A multi-center clinical trial is proposed to evaluate the method's ability to predict bone marrow results in patients with cytopenia, potentially reducing reliance on bone marrow biopsies.
Primary Outcome
Comparison between PERIBLOOD-MDS diagnosis and bone marrow evaluation of MDS
Conditions Studied
Interventions
- DIAGNOSTIC_TEST PERIBLOOD
Study Locations (2)
California
- University of California San Diego - San Diego
Florida
- University of Miami - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,500 participants |
| Start Date | 2025-06-01 |
| Est. Completion | 2028-12 |
What NCT07081087 shows while recruiting
NCT07081087 is an observational study that tracks outcomes without assigning an intervention. Its 1,500 participants enrollment target places it among the larger protocols in the corpus, above the 243-participant average among 11 other Cytopenia trials with a reported enrollment target (517% higher).
The record links to 1 condition, with Cytopenia appearing as the primary indexed condition, and to 1 intervention - of which PERIBLOOD is the first listed.
NCT07081087 reports a single indexed study location in California, Florida.
Frequently Asked Questions
What is clinical trial NCT07081087 about?
NCT07081087 is a clinical study titled "Development of a Peripheral Blood Assay to Replace BM Evaluation in Cytopenia - a Multi-Center Observational Study". This study aims to validate a novel, non-invasive diagnostic approach for blood and bone marrow malignancies using single-cell RNA sequencing of circulating hematopoietic stem and progenitor cells (cHSPCs) from peripheral blood. Building on prior work defining normal cHSPC profiles in healthy indivi...
What is the current status of trial NCT07081087?
This trial is currently recruiting. The enrollment target is 1,500 participants. The study started on 2025-06-01. Estimated completion is 2028-12.
What conditions does trial NCT07081087 study?
This clinical trial studies the following conditions: Cytopenia.
What interventions are being tested in trial NCT07081087?
The interventions under investigation include: PERIBLOOD (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07081087?
This trial is sponsored by Weizmann Institute of Science, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07081087 being conducted?
This trial has 2 study locations across California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cytopenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07081087's enrollment target sits among peer trials
1,500 2nd of 11 the highest of 11 other Cytopenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cytopenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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