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ACTIVE NOT RECRUITING Phase 3

A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection

NCT06903338 · View on ClinicalTrials.gov ↗

Study Summary

This is a multicenter, open label, randomized Phase 3 clinical study to evaluate the efficacy and safety of the combination of tobevibart + elebsiran for the treatment of chronic hepatitis delta in comparison to delayed treatment.

Conditions Studied

Interventions

  • DRUG Tobevibart
  • DRUG Elebsiran

Study Locations (20)

Other

  • Investigative Site — Montreal
  • Investigative Site — Ottawa
  • Investigative Site — Québec
  • Investigative Site — Vancouver
  • Investigative Site — Tbilisi

California

  • Investigative Site — Los Angeles
  • Investigative Site — Redwood City
  • Investigative Site — San Francisco

New York

  • Investigative Site — New York
  • Investigative Site — New York
  • Investigative Site — New York

Arizona

  • Investigative Site — Chandler

Florida

  • Investigative Site — DeLand

Illinois

  • Investigative Site — Chicago

Maryland

  • Investigative Site — Baltimore

New Jersey

  • Investigative Site — Hillsborough

Trial Details

FieldValue
Enrollment Target 124 participants
Start Date 2025-03-12
Est. Completion 2031-05
Phase Phase 3

Sponsor

Vir Biotechnology

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06903338

The ClinicalTrials.gov registry entry for NCT06903338 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 124 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vir Biotechnology, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Viral Hepatitis appearing as the primary indexed condition, and to 2 interventions — of which Tobevibart is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06903338 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Other, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06903338 about?

NCT06903338 is a clinical study titled "A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection". This is a multicenter, open label, randomized Phase 3 clinical study to evaluate the efficacy and safety of the combination of tobevibart + elebsiran for the treatment of chronic hepatitis delta in comparison to delayed treatment.

What is the current status of trial NCT06903338?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 124 participants. The study started on 2025-03-12. Estimated completion is 2031-05.

What conditions does trial NCT06903338 study?

This clinical trial studies the following conditions: Viral Hepatitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06903338?

The interventions under investigation include: Tobevibart (DRUG), Elebsiran (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06903338?

This trial is sponsored by Vir Biotechnology, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06903338 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial