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RECRUITING

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

NCT06883240 · View on ClinicalTrials.gov ↗

Study Summary

This non-interventional study (NIS) is designed to collect information on the effectiveness and safety of treatment received in routine clinical care, as well as measure the health-related quality of life (HRQoL) of participants with Type 3 von Willebrand disease (VWD) receiving prophylactic therapy per local standard of care (SOC) over an observation period of at least 24 weeks.

Interventions

  • DRUG Von Willebrand Factor Concentrates
  • DRUG Von Willebrand Factor Concentrates and Factor VIII Concentrates
  • DRUG Factor VIII Concentrates
  • DRUG Recombinant Activated Factor VII
  • DRUG Activated Prothrombin Complex Concentrate

Study Locations (20)

Other

  • UZ Leuven Gasthuisberg — Leuven
  • IPS SURA Industriales Medellín — Medellín
  • Hopital Claude Huriez - CHU Lille — Lille
  • Groupe Hospitalier Necker Enfants Malades — Paris
  • Universitätsklinikum Bonn — Bonn
  • Gerinnungszentrum Rhein-Ruhr;Gerinnungsambulanz — Duisburg
  • Hämophiliezentrum Med. Klinik III/Institut für Transfusionsmedizin — Frankfurt/M.
  • Kurume University Hospital — Fukuoka
  • Tokyo Medical University Hospital — Tokyo
  • Erasmus MC — Rotterdam
  • Instytut Hematologii i Transfuzjologii — Warsaw

California

  • UC Davis — Sacramento

Florida

  • University of Florida — Gainesville

Minnesota

  • University of Minnesota Medical Center — Minneapolis

Missouri

  • Washington University School of Medicine — St Louis

Ontario

  • The Hospital for Sick Children — Toronto

Quebec

  • McGill University Health Center — Montreal

Lazio

  • Universita' Degli Studi La Sapienza-Ist.Di Ematologia — Rome

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-04-29
Est. Completion 2026-11-01

Sponsor

Hoffmann-La Roche

758 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06883240

The ClinicalTrials.gov registry entry for NCT06883240 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 758 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Von Willebrand Disease, Type 3 appearing as the primary indexed condition, and to 5 interventions — of which Von Willebrand Factor Concentrates is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06883240 reports 20 study locations spanning 10 distinct geographic areas — top geographies include Other, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06883240 about?

NCT06883240 is a clinical study titled "An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment". This non-interventional study (NIS) is designed to collect information on the effectiveness and safety of treatment received in routine clinical care, as well as measure the health-related quality of life (HRQoL) of participants with Type 3 von Willebrand disease (VWD) receiving prophylactic therapy...

What is the current status of trial NCT06883240?

This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2025-04-29. Estimated completion is 2026-11-01.

What conditions does trial NCT06883240 study?

This clinical trial studies the following conditions: Von Willebrand Disease, Type 3. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06883240?

The interventions under investigation include: Von Willebrand Factor Concentrates (DRUG), Von Willebrand Factor Concentrates and Factor VIII Concentrates (DRUG), Factor VIII Concentrates (DRUG), Recombinant Activated Factor VII (DRUG), Activated Prothrombin Complex Concentrate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06883240?

This trial is sponsored by Hoffmann-La Roche, which has 758 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06883240 being conducted?

This trial has 20 study locations across California, Florida, Minnesota, Missouri, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial