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Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty
NCT06831422 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this randomized controlled trial is to determine the effect of post-incision wash using various novel antimicrobial solutions on the rate of positive C. Acnes cultures collected from adults undergoing primary shoulder replacement surgery. Subjects will be randomly assigned in a 1:1:1:1 fashion to groups that will receive one of the following treatments: * Post-incision application of Xperience Antimicrobial wash (NextScience, Jacksonville, FL) * Post-incision application of 3% hydrogen peroxide * Post-incision application of 10% povidone-iodine (betadine) * No post-incision treatment (control) The investigators hypothesize that the subjects treated with the antimicrobial solutions after initial incision will have lower rates of positive C. Acnes cultures. The investigators also hypothesize that post-incision application of Xperience Antimicrobial wash and Betadine will have an equal reduction in the incidence of C. acnes as Hydrogen Peroxide.
Conditions Studied
Interventions
- DEVICE Povidone-Iodine
- DEVICE Hydrogen Peroxide
- DEVICE Xperience Antimicrobial Wash
- DIAGNOSTIC_TEST Bacterial Cultures
- PROCEDURE Shoulder Arthroplasty
Study Locations (1)
Michigan
- Henry Ford Health — Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2025-05-05 |
| Est. Completion | 2027-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06831422
The ClinicalTrials.gov registry entry for NCT06831422 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Henry Ford Health System, which has 171 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Shoulder Arthroplasty appearing as the primary indexed condition, and to 5 interventions — of which Povidone-Iodine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06831422 reports 1 study location spanning 1 distinct geographic area — top geographies include Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06831422 about?
NCT06831422 is a clinical study titled "Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty". The purpose of this randomized controlled trial is to determine the effect of post-incision wash using various novel antimicrobial solutions on the rate of positive C. Acnes cultures collected from adults undergoing primary shoulder replacement surgery. Subjects will be randomly assigned in a 1:1:1:...
What is the current status of trial NCT06831422?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2025-05-05. Estimated completion is 2027-09.
What conditions does trial NCT06831422 study?
This clinical trial studies the following conditions: Shoulder Arthroplasty, Positive C. Acnes Culture. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06831422?
The interventions under investigation include: Povidone-Iodine (DEVICE), Hydrogen Peroxide (DEVICE), Xperience Antimicrobial Wash (DEVICE), Bacterial Cultures (DIAGNOSTIC_TEST), Shoulder Arthroplasty (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06831422?
This trial is sponsored by Henry Ford Health System, which has 171 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06831422 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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