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NCT06809348 · ClinicalTrials.gov registry record · NA

Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention

A NA study of Suicidal Thoughts and Behaviors, sponsored by University of California, San Diego.

Recruiting
Registry status
NA
Development phase
70
Enrollment target
1
Study location

NCT06809348 is a NA study of Suicidal Thoughts and Behaviors that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 70 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT06809348, a NA study of Suicidal Thoughts and Behaviors, is actively recruiting participants, sponsored by University of California, San Diego.

RECRUITING
Registry status
NA
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual. Despite these differences, most treatments for suicidal thoughts assume that the same intervention works equally well for all individuals at high-risk of suicide. Intensive longitudinal data combined with network science, integrated with coaching, could be used to personalize suicide prevention interventions to make them more effective and efficient. This K23 Career Development application involves refining and testing a novel personalized treatment for individuals at high-risk called PeRsonalizEd Clinical Intervention for Suicidal Events or PRECISE. PRECISE leverages idiographic statistical techniques adopted from network science applied to ecological momentary assessment data to inform the tailoring of Safety Planning and skills from Dialectical Behavior Therapy, two existing evidence-based treatments for suicide. In Aim 1, a user-centered design approach will be used to refine PRECISE. Following the refinement of the intervention, informed by data from a case series in Aim 1, the investigators will then conduct a randomized controlled trial comparing two different intensities of personalization. In the low-intensity arm, the 8-week treatment will be tailored based on an initial two-week burst of ecological momentary assessment and one idiographic model. In the high-intensity arm, participants complete eight weeks of ecological momentary assessment and idiographic models are generated between each session. Coaches use the idiographic models to identify an individuals' drivers of suicidal thoughts and conduct behavioral chain analyses to tailor specific skills to then teach, shape, and reinforce in their individual clients. Assessments are completed pre-treatment, 8-weeks post-enrollment, and 16-weeks enrollment. The investigators hypothesize that both arms will demonstrate clinically significant reductions in suicidal

Interventions

  • BEHAVIORAL PRECISE

Study Locations (1)

California

  • 8980 Villa La Jolla Drive - San Diego

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2025-11-14
Est. Completion 2030-03
Phase NA

Sponsor

University of California, San Diego

775 total trials

What the Registry Record Tells You About NCT06809348

The ClinicalTrials.gov registry entry for NCT06809348 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Suicidal Thoughts and Behaviors appearing as the primary indexed condition, and to 1 intervention - of which PRECISE is the first listed.

NCT06809348 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06809348 about?

NCT06809348 is a clinical study titled "Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention". Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual. Despite these differences, most treatments for suicidal thoughts assume that the same intervention works equally well for all individuals at high-risk o...

What is the current status of trial NCT06809348?

This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2025-11-14. Estimated completion is 2030-03.

What conditions does trial NCT06809348 study?

This clinical trial studies the following conditions: Suicidal Thoughts and Behaviors.

What interventions are being tested in trial NCT06809348?

The interventions under investigation include: PRECISE (BEHAVIORAL).

Who is sponsoring clinical trial NCT06809348?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06809348 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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