Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 3

Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

NCT06790784 · View on ClinicalTrials.gov ↗

Study Summary

This randomized trial will compare treatment strategies for proliferative diabetic retinopathy (PDR). Participants will receive either combination a of faricimab + PRP or vitrectomy + endolaser. The participants will be followed for 3 years. The study will evaluate long-term visual acuity as well as differences in number of injections, procedures, and complications during follow-up (after completion of randomization treatment), and cost.

Interventions

  • DRUG Faricimab
  • PROCEDURE Vitrectomy
  • DEVICE Endolaser
  • DEVICE Panretinal Photocoagulation (PRP)

Study Locations (20)

Florida

  • Florida Retina Consultants — Lakeland
  • Ophthalmic Partners of Florida, PA dba Central Florida Retina — Orlando
  • Retina Associates of Florida, LLC — Tampa

California

  • Retina Associates of Southern California — Huntington Beach
  • Loma Linda University — Loma Linda

Massachusetts

  • Boston Medical Center Corporation — Boston
  • Joslin Diabetes Center — Boston

Texas

  • Retina Consultants of Texas, PA — Bellaire
  • Texas Retina Associates — Lubbock

Georgia

  • Southeast Retina Center, P.C. — Augusta

Illinois

  • Illinois Retina Associates SC Oak Park Site — Oak Park

Indiana

  • Midwest Eye Institute — Carmel

Iowa

  • Wolfe Clinic, P.C.- West Des Moines — West Des Moines

Trial Details

FieldValue
Enrollment Target 426 participants
Start Date 2025-08-04
Est. Completion 2031-08
Phase Phase 3

Sponsor

Jaeb Center for Health Research

134 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06790784

The ClinicalTrials.gov registry entry for NCT06790784 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 426 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jaeb Center for Health Research, which has 134 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Proliferative Diabetic Retinopathy (PDR) appearing as the primary indexed condition, and to 4 interventions — of which Faricimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06790784 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Florida, California, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06790784 about?

NCT06790784 is a clinical study titled "Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR". This randomized trial will compare treatment strategies for proliferative diabetic retinopathy (PDR). Participants will receive either combination a of faricimab + PRP or vitrectomy + endolaser. The participants will be followed for 3 years. The study will evaluate long-term visual acuity as well as...

What is the current status of trial NCT06790784?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 426 participants. The study started on 2025-08-04. Estimated completion is 2031-08.

What conditions does trial NCT06790784 study?

This clinical trial studies the following conditions: Proliferative Diabetic Retinopathy (PDR). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06790784?

The interventions under investigation include: Faricimab (DRUG), Vitrectomy (PROCEDURE), Endolaser (DEVICE), Panretinal Photocoagulation (PRP) (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06790784?

This trial is sponsored by Jaeb Center for Health Research, which has 134 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06790784 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial