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NCT06702449 · ClinicalTrials.gov registry record · Phase 1
A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age
A Phase 1 study of Urinary Tract Infections, sponsored by GlaxoSmithKline.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 448
- Enrollment target
- 8
- Study locations
NCT06702449: Recruiting Phase 1 study of Urinary Tract Infections, sponsored by GlaxoSmithKline.
NCT06702449 is a Phase 1 study of Urinary Tract Infections that is actively recruiting participants, run by GlaxoSmithKline. The registered enrollment target is 448 participants, roughly in line with the 445-participant average among 34 other Urinary Tract Infections trials with a reported enrollment target. The trial reports 8 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06702449, a Phase 1 study of Urinary Tract Infections, is actively recruiting participants, sponsored by GlaxoSmithKline.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 448 participants
- Enrollment target
- 8
- Study locations
Study Summary
The purpose of this study is to assess safety, reactogenicity, and immune response of the candidate UTI vaccine compared to placebo in adults between and including 18-64 years of age (YOA), and to perform a preliminary evaluation of clinical efficacy in females between and including 18-64 YOA.
Primary Outcome
Solicited administration site events include pain, redness and swelling at administration site.
Conditions Studied
Interventions
- COMBINATION_PRODUCT Candidate UTI vaccine low dose formulation 1
- COMBINATION_PRODUCT Candidate UTI vaccine low dose formulation 2
- COMBINATION_PRODUCT Candidate UTI vaccine medium dose formulation 1
- COMBINATION_PRODUCT Candidate UTI vaccine medium dose formulation 2
- COMBINATION_PRODUCT Candidate UTI vaccine high dose formulation 1
Study Locations (8)
Washington
- GSK Investigational Site - Seattle
- GSK Investigational Site - Wenatchee
Other
- GSK Investigational Site - Johannesburg
- GSK Investigational Site - Soshanguve
Kansas
- GSK Investigational Site - Lenexa
New Jersey
- GSK Investigational Site - Secaucus
New York
- GSK Investigational Site - Rochester
Texas
- GSK Investigational Site - Weatherford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 448 participants |
| Start Date | 2024-11-19 |
| Est. Completion | 2027-05-31 |
| Phase | Phase 1 |
What NCT06702449 shows while recruiting
NCT06702449 is an interventional study that assigns participants to a tested intervention. The registered 448 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 445-participant average among 34 other Urinary Tract Infections trials with a reported enrollment target.
The record links to 1 condition, with Urinary Tract Infections appearing as the primary indexed condition, and to 5 interventions - of which Candidate UTI vaccine low dose formulation 1 is the first listed.
NCT06702449 lists 8 locations in 6 states (Washington, Other, Kansas).
Frequently Asked Questions
What is clinical trial NCT06702449 about?
NCT06702449 is a clinical study titled "A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age". The purpose of this study is to assess safety, reactogenicity, and immune response of the candidate UTI vaccine compared to placebo in adults between and including 18-64 years of age (YOA), and to perform a preliminary evaluation of clinical efficacy in females between and including 18-64 YOA.
What is the current status of trial NCT06702449?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 448 participants. The study started on 2024-11-19. Estimated completion is 2027-05-31.
What conditions does trial NCT06702449 study?
This clinical trial studies the following conditions: Urinary Tract Infections.
What interventions are being tested in trial NCT06702449?
The interventions under investigation include: Candidate UTI vaccine low dose formulation 1 (COMBINATION_PRODUCT), Candidate UTI vaccine low dose formulation 2 (COMBINATION_PRODUCT), Candidate UTI vaccine medium dose formulation 1 (COMBINATION_PRODUCT), Candidate UTI vaccine medium dose formulation 2 (COMBINATION_PRODUCT), Candidate UTI vaccine high dose formulation 1 (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT06702449?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06702449 being conducted?
This trial has 8 study locations across Kansas, New Jersey, New York, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Urinary Tract Infections
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Where NCT06702449's enrollment target sits among peer trials
448 9th of 34 higher than 26 of 34 other Urinary Tract Infections trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Urinary Tract Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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