Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06692686 · ClinicalTrials.gov registry record · NA
AFO Prescription to Optimize Post-Stroke Function
A NA study of Stroke Patients and Ankle Foot Orthosis (AFO), sponsored by University of Texas at Austin.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 4
- Study locations
NCT06692686: Recruiting NA study of Stroke Patients and Ankle Foot Orthosis (AFO), sponsored by University of Texas at Austin.
NCT06692686 is a NA study of Stroke Patients and Ankle Foot Orthosis (AFO) that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 120 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06692686, a NA study of Stroke Patients and Ankle Foot Orthosis (AFO), is actively recruiting participants, sponsored by University of Texas at Austin.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 4
- Study locations
Study Summary
The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis (AFO) treatment options targeting the rehabilitation of individuals post-stroke. To achieve this goal, the investigators will: 1. Identify the factors that significantly contribute to an individual's highest potential quality of life when considering each of the three available AFO design options, and 2. Develop prediction models of clinical performance using biomechanical function linked to the three AFO designs. Participants will be asked to: * Wear each of the three modern AFO designs for one month, after receiving therapy training and * Complete questionnaires and performance tests with each AFO. In addition, the subset of individuals participating in goal 2) will also be asked to: * Perform biomechanical analyses using high-speed cameras and force plates during different walking and balance tests with each AFO design.
Primary Outcome
Health-related quality of life (HRQoL) is a framework that considers physical, mental, emotional, and social function when assessing the satisfaction of AFO users with their AFO.
Conditions Studied
Interventions
- DEVICE Pre-fabricated (PF) ankle-foot orthosis (AFO)
- DEVICE Carbon-strut (CS) ankle-foot orthosis (AFO)
- DEVICE Multifunctional articulating (MA) ankle-foot orthosis (AFO)
Study Locations (4)
California
- Rancho Research Institute - Downey
Florida
- Brooks Rehabilitation - Jacksonville
South Carolina
- Medical University of South Carolina - Charleston
Texas
- Hanger Clinic - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-07-08 |
| Est. Completion | 2027-10 |
| Phase | NA |
What NCT06692686 shows while recruiting
NCT06692686 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).
The record links to 3 conditions, with Stroke Patients appearing as the primary indexed condition, and to 3 interventions - of which Pre-fabricated (PF) ankle-foot orthosis (AFO) is the first listed.
NCT06692686 reports a single indexed study location in California, Florida, South Carolina.
Frequently Asked Questions
What is clinical trial NCT06692686 about?
NCT06692686 is a clinical study titled "AFO Prescription to Optimize Post-Stroke Function". The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis (AFO) treatment options targeting the rehabilitation of individuals po...
What is the current status of trial NCT06692686?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-07-08. Estimated completion is 2027-10.
What conditions does trial NCT06692686 study?
This clinical trial studies the following conditions: Stroke Patients, Ankle Foot Orthosis (AFO), Post-Stroke Hemiparesis.
What interventions are being tested in trial NCT06692686?
The interventions under investigation include: Pre-fabricated (PF) ankle-foot orthosis (AFO) (DEVICE), Carbon-strut (CS) ankle-foot orthosis (AFO) (DEVICE), Multifunctional articulating (MA) ankle-foot orthosis (AFO) (DEVICE).
Who is sponsoring clinical trial NCT06692686?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06692686 being conducted?
This trial has 4 study locations across California, Florida, South Carolina, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke Patients
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06692686's enrollment target sits among peer trials
120 762nd of 2000 higher than 1,198 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01174108 · 120 participants · Phase 2
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
- NCT01627301 · 120 participants · NA
Sympathetic Overactivity in Post-traumatic Stress Disorder
- NCT02025023 · 120 participants · Phase 3
Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study
- NCT02128906 · 120 participants · Phase 2
Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI