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AFO Prescription to Optimize Post-Stroke Function
NCT06692686 · View on ClinicalTrials.gov ↗
Study Summary
The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis (AFO) treatment options targeting the rehabilitation of individuals post-stroke. To achieve this goal, the investigators will: 1. Identify the factors that significantly contribute to an individual's highest potential quality of life when considering each of the three available AFO design options, and 2. Develop prediction models of clinical performance using biomechanical function linked to the three AFO designs. Participants will be asked to: * Wear each of the three modern AFO designs for one month, after receiving therapy training and * Complete questionnaires and performance tests with each AFO. In addition, the subset of individuals participating in goal 2) will also be asked to: * Perform biomechanical analyses using high-speed cameras and force plates during different walking and balance tests with each AFO design.
Conditions Studied
Interventions
- DEVICE Pre-fabricated (PF) ankle-foot orthosis (AFO)
- DEVICE Carbon-strut (CS) ankle-foot orthosis (AFO)
- DEVICE Multifunctional articulating (MA) ankle-foot orthosis (AFO)
Study Locations (4)
California
- Rancho Research Institute — Downey
Florida
- Brooks Rehabilitation — Jacksonville
South Carolina
- Medical University of South Carolina — Charleston
Texas
- Hanger Clinic — Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-07-08 |
| Est. Completion | 2027-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06692686
The ClinicalTrials.gov registry entry for NCT06692686 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas at Austin, which has 225 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Stroke Patients appearing as the primary indexed condition, and to 3 interventions — of which Pre-fabricated (PF) ankle-foot orthosis (AFO) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06692686 reports 4 study locations spanning 4 distinct geographic areas — top geographies include California, Florida, South Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06692686 about?
NCT06692686 is a clinical study titled "AFO Prescription to Optimize Post-Stroke Function". The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis (AFO) treatment options targeting the rehabilitation of individuals po...
What is the current status of trial NCT06692686?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-07-08. Estimated completion is 2027-10.
What conditions does trial NCT06692686 study?
This clinical trial studies the following conditions: Stroke Patients, Ankle Foot Orthosis (AFO), Post-Stroke Hemiparesis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06692686?
The interventions under investigation include: Pre-fabricated (PF) ankle-foot orthosis (AFO) (DEVICE), Carbon-strut (CS) ankle-foot orthosis (AFO) (DEVICE), Multifunctional articulating (MA) ankle-foot orthosis (AFO) (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06692686?
This trial is sponsored by University of Texas at Austin, which has 225 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06692686 being conducted?
This trial has 4 study locations across California, Florida, South Carolina, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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