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RECRUITING Phase 1

Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors

NCT06667141 · View on ClinicalTrials.gov ↗

Study Summary

This is a first in-human, Open-label Phase 1 study to assess the safety of ACR-2316 for the treatment of subjects with specific, histologically confirmed, locally advanced, recurrent or metastatic solid tumors.

Interventions

  • DRUG ACR-2316

Study Locations (15)

California

  • Precision NextGen Oncology & Research Center — Beverly Hills
  • Hoag Memorial Hospital Presbyterian — Newport Beach

New York

  • Roswell Park Comprehensive Cancer Center — Buffalo
  • Montefiore Medical Centre — The Bronx

Texas

  • The University of Texas MD Anderson Cancer Center — Houston
  • NEXT Oncology — San Antonio

Arizona

  • HonorHealth Research Institute — Phoenix

Colorado

  • Denver Health One — Denver

Florida

  • Florida Cancer Specialist — Sarasota

Massachusetts

  • Beth Israel Deaconess Medical Center — Boston

Michigan

  • University of Michigan — Ann Arbor

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2024-10-08
Est. Completion 2026-12-12
Phase Phase 1

Sponsor

Acrivon Therapeutics

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06667141

The ClinicalTrials.gov registry entry for NCT06667141 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Acrivon Therapeutics, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Specific Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which ACR-2316 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06667141 reports 15 study locations spanning 12 distinct geographic areas — top geographies include California, New York, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06667141 about?

NCT06667141 is a clinical study titled "Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors". This is a first in-human, Open-label Phase 1 study to assess the safety of ACR-2316 for the treatment of subjects with specific, histologically confirmed, locally advanced, recurrent or metastatic solid tumors.

What is the current status of trial NCT06667141?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2024-10-08. Estimated completion is 2026-12-12.

What conditions does trial NCT06667141 study?

This clinical trial studies the following conditions: Specific Advanced Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06667141?

The interventions under investigation include: ACR-2316 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06667141?

This trial is sponsored by Acrivon Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06667141 being conducted?

This trial has 15 study locations across Arizona, California, Colorado, Florida, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial