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NCT06641466 · ClinicalTrials.gov registry record · Phase 3
A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine
A Phase 3 study of Menstrual Migraine, sponsored by Pfizer.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 723
- Enrollment target
- 20
- Study locations
NCT06641466: Recruiting Phase 3 study of Menstrual Migraine, sponsored by Pfizer.
NCT06641466 is a Phase 3 study of Menstrual Migraine that is actively recruiting participants, run by Pfizer. The registered enrollment target is 723 participants, above the 42-participant average among 3 other Menstrual Migraine trials with a reported enrollment target (1621% higher). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06641466, a Phase 3 study of Menstrual Migraine, is actively recruiting participants, sponsored by Pfizer.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 723 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate the efficacy and safety of rimegepant when administered during the peri-menstrual period (PMP) for intermittent prevention of migraine in women who experience menstrual migraine attacks.
Primary Outcome
Change from Observation Period in the number of migraine days per the 5-day perimenstrual period
Conditions Studied
Interventions
- DRUG Standard of Care
- DRUG Placebo Comparator
- DRUG Rimegepant
Study Locations (20)
Arizona
- Mayo Clinic Hospital - Phoenix
- Mayo Clinic Specialty Building - Phoenix
- Mayo Clinic Arizona - Scottsdale
California
- Hope Clinical Research, Inc. - Canoga Park
- Axiom Research - Colton
- Diablo Clinical Research, Inc. - Walnut Creek
Florida
- VIN - Aventura - Aventura
- Velocity Clinical Research, Hallandale Beach - Hallandale
- Jacksonville Center for Clinical Research - Jacksonville
Georgia
- Urban Family Practice Associates - Marietta
- Clinical Research Atlanta - Stockbridge
Missouri
- Clinvest Headlands Llc - Springfield
- St. Charles Clinical Research - Weldon Spring
New York
- Rochester Clinical Research, LLC - Rochester
- Montefiore Medical Center - The Bronx
Idaho
- St Luke's Clinic - Neurology - Meridian
Indiana
- Alliance for Multispecialty Research - Medisphere Medical Research Center - Evansville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 723 participants |
| Start Date | 2025-03-11 |
| Est. Completion | 2027-03-30 |
| Phase | Phase 3 |
What NCT06641466 shows while recruiting
NCT06641466 is an interventional study that assigns participants to a tested intervention. The registered 723 participants enrollment target is mid-sized for trials with a published cap, above the 42-participant average among 3 other Menstrual Migraine trials with a reported enrollment target (1621% higher).
The record links to 1 condition, with Menstrual Migraine appearing as the primary indexed condition, and to 3 interventions - of which Standard of Care is the first listed.
NCT06641466 names 20 study sites across 11 states, led by Arizona, California, Florida.
Frequently Asked Questions
What is clinical trial NCT06641466 about?
NCT06641466 is a clinical study titled "A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine". The purpose of this study is to evaluate the efficacy and safety of rimegepant when administered during the peri-menstrual period (PMP) for intermittent prevention of migraine in women who experience menstrual migraine attacks.
What is the current status of trial NCT06641466?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 723 participants. The study started on 2025-03-11. Estimated completion is 2027-03-30.
What conditions does trial NCT06641466 study?
This clinical trial studies the following conditions: Menstrual Migraine.
What interventions are being tested in trial NCT06641466?
The interventions under investigation include: Standard of Care (DRUG), Placebo Comparator (DRUG), Rimegepant (DRUG).
Who is sponsoring clinical trial NCT06641466?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06641466 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Georgia, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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