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A Study on the Safety and Immune Response to an mRNA-based RSV Investigational Vaccine in Healthy Adults Aged 18-45 Years
NCT06573281 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to assess the reactogenicity, safety and immune response of various formulations of the RSV mRNA investigational vaccine administered in healthy participants 18-45 years of age.
Conditions Studied
Interventions
- BIOLOGICAL Investigational RSV vaccine 1
- BIOLOGICAL Investigational RSV vaccine 2
- BIOLOGICAL Investigational RSV vaccine 3
- BIOLOGICAL Investigational RSV vaccine 4
- BIOLOGICAL Investigational RSV vaccine 5
Study Locations (9)
Other
- GSK Investigational Site — Madrid
- GSK Investigational Site — Madrid
- GSK Investigational Site — Madrid
California
- GSK Investigational Site — Rolling Hills Estates
Georgia
- GSK Investigational Site — Atlanta
Kansas
- GSK Investigational Site — Lenexa
Nebraska
- GSK Investigational Site — Omaha
New York
- GSK Investigational Site — Rochester
Victoria
- GSK Investigational Site — Camberwell
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 213 participants |
| Start Date | 2024-09-30 |
| Est. Completion | 2026-04-13 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06573281
The ClinicalTrials.gov registry entry for NCT06573281 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 213 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Respiratory Syncytial Virus Infections appearing as the primary indexed condition, and to 5 interventions — of which Investigational RSV vaccine 1 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06573281 reports 9 study locations spanning 7 distinct geographic areas — top geographies include Other, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06573281 about?
NCT06573281 is a clinical study titled "A Study on the Safety and Immune Response to an mRNA-based RSV Investigational Vaccine in Healthy Adults Aged 18-45 Years". The purpose of this study is to assess the reactogenicity, safety and immune response of various formulations of the RSV mRNA investigational vaccine administered in healthy participants 18-45 years of age.
What is the current status of trial NCT06573281?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 213 participants. The study started on 2024-09-30. Estimated completion is 2026-04-13.
What conditions does trial NCT06573281 study?
This clinical trial studies the following conditions: Respiratory Syncytial Virus Infections. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06573281?
The interventions under investigation include: Investigational RSV vaccine 1 (BIOLOGICAL), Investigational RSV vaccine 2 (BIOLOGICAL), Investigational RSV vaccine 3 (BIOLOGICAL), Investigational RSV vaccine 4 (BIOLOGICAL), Investigational RSV vaccine 5 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06573281?
This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06573281 being conducted?
This trial has 9 study locations across California, Georgia, Kansas, Nebraska, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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